Molecular and clinical heterogeneity within MYC-family amplified medulloblastoma is associated with survival outcomes: A multicenter cohort study

Edward C Schwalbe,  Janet C Lindsey,  Marina Danilenko,  Rebecca M Hill,  Stephen Crosier,  Sarra L Ryan,  Daniel Williamson,  Jemma Castle,  Debbie Hicks,  Marcel Kool,  Till Milde,  Andrey Korshunov,  Stefan M Pfister,  Simon Bailey,  Steven C Clifford.

Neuro-Oncology
Volume: 27, Issue: 1, Pages: 222-236.

Stratified Medicine Paediatrics: Cell free DNA and serial tumour sequencing identifies subtype specific cancer evolution and epigenetic states

Sally L. George,  Claire Lynn,  Reda Stankunaite,  Debbie Hughes,  Carolin M. Sauer,  Jane Chalker,  Saira Waqar Ahmed,  Minou Oostveen,  Paula Z. Proszek,  Lina Yuan,  Ridwan Shaikh,  Sabri Jamal,  Ama Brew,  Jennifer Tall,  Tony Rogers,  Steven C. Clifford,  Josef Vormoor,  Janet M. Shipley,  Deborah A. Tweddle,  Chris Jones,  Courtney Willis,  G.A. Amos Burke,  Aditi Vedi,  Lisa Howell,  Robert Johnston,  Helen Rees,  Madeleine Adams,  Angela Jesudason,  Milind Ronghe,  Martin Elliott,  Emma Ross,  Guy Makin,  Quentin Campbell-Hewson,  Richard G. Grundy,  Jennifer Turnbull,  Shaun Wilson,  Victoria Lee,  Juliet C. Gray,  Sara Stoneham,  Susanne A. Gatz,  Lynley V. Marshall,  Paola Angelini,  John Anderson,  George D. Cresswell,  Trevor A. Graham,  Bissan Al-Lazikani,  Isidro Cortes-Ciriano,  Pamela Kearns,  J. Ciaran Hutchinson,  Darren Hargrave,  Thomas S. Jacques,  Michael Hubank,  Andrea Sottoriva,  Louis Chesler.

Cancer Discovery

Replenishing co-downregulated miR-100-5p and miR-125b-5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

Marta Ferraresso,  Shivani Bailey,  Luz Alonso-Crisostomo,  Dawn Ward,  Christos Panayi,  Zachary G. L. Scurlock,  Harpreet K. Saini,  Stephen P. Smith,  James C. Nicholson,  Anton J. Enright,  Cinzia G. Scarpini,  Nicholas Coleman,  Matthew J. Murray.

Molecular Oncology

Paediatric bone marrow mesenchymal stem cells support acute myeloid leukaemia cell survival and enhance chemoresistance via contact-independent mechanism

Alison Laing,  Ahmed Elmarghany,  Arwa A. Alghaith,  Aya Gouma,  Thomas Stevens,  Alexander Winton,  Jennifer Cassels,  Cassie J. Clarke,  Claire Schwab,  Christine J. Harrison,  Brenda Gibson,  Karen Keeshan.

British Journal of Haematology
Volume: n/a, Issue: n/a.

The fetal specific gene LIN28B is essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia | bioRxiv

Rebecca Ling,  Thomas Jackson,  Natalina Elliot,  Joe Cross,  Lucy Hamer,  Arundhati Wuppalapati,  Alastair Smith,  Catherine Chahrour,  Okan Sevim,  Deena Iskander,  Guanlin Wang,  Siobhan Rice,  Sorcha O'Byrne,  Joe Harman,  Bethan Psaila,  Rhys Morgan,  Irene Roberts,  Thomas A. Milne,  Anindita Roy.

Novel immunotherapeutics against LGR5 to target multiple cancer types

Hung-Chang Chen,  Nico Mueller,  Katherine Stott,  Chrysa Kapeni,  Eilidh Rivers,  Carolin M Sauer,  Flavio Beke,  Stephen J Walsh,  Nicola Ashman,  Louise O’Brien,  Amir Rafati Fard,  Arman Ghodsinia,  Changtai Li,  Fadwa Joud,  Olivier Giger,  Inti Zlobec,  Ioana Olan,  Sarah J Aitken,  Matthew Hoare,  Richard Mair,  Eva Serrao,  James D Brenton,  Alicia Garcia-Gimenez,  Simon E Richardson,  Brian Huntly,  David R Spring,  Mikkel-Ole Skjoedt,  Karsten Skjødt,  Marc de la Roche,  Maike de la Roche.

EMBO Molecular Medicine
Volume: 16, Issue: 9, Pages: 2233-2261.

Recurrent adamantinomatous craniopharyngiomas show MAPK pathway activation, clonal evolution and rare TP53-loss-mediated malignant progression

John R. Apps,  Jose Mario Gonzalez-Meljem,  Romain Guiho,  Jessica C. Pickles,  Eric Prince,  Edward Schwalbe,  Nikhil Joshi,  Thomas J. Stone,  Olumide Ogunbiyi,  Jane Chalker,  Akang Bassey,  Georg Otto,  Rosalind Davies,  Debbie Hughes,  Sebastian Brandner,  Enrica Tan,  Victoria Lee,  Caroline Hayhurst,  Cassie Kline,  Sergi Castellano,  Todd Hankinson,  Timo Deutschbein,  Thomas S. Jacques,  Juan Pedro Martinez-Barbera.

Acta Neuropathologica Communications
Volume: 12.

Noncoding mutations drive persistence of a founder preleukemic clone which initiates late relapse in T-ALL

David O’Connor,  Jose Espejo Valle-Inclán,  Lucia Conde,  Gianna Bloye,  Sunniyat Rahman,  Joana R. Costa,  Jack Bartram,  Stuart Adams,  Gary Wright,  Hillary Elrick,  Kerry Wall,  Sara Dyer,  Christopher Howell,  Galina Jigoulina,  Javier Herrero,  Isidro Cortes-Ciriano,  Anthony V. Moorman,  Marc R. Mansour.

Blood
Volume: 143, Issue: 10, Pages: 933-937.

Noncoding mutations drive persistence of a founder preleukemic clone which initiates late relapse in T-ALL

David O’Connor,  Jose Espejo Valle-Inclán,  Lucia Conde,  Gianna Bloye,  Sunniyat Rahman,  Joana R. Costa,  Jack Bartram,  Stuart Adams,  Gary Wright,  Hillary Elrick,  Kerry Wall,  Sara Dyer,  Christopher Howell,  Galina Jigoulina,  Javier Herrero,  Isidro Cortes-Ciriano,  Anthony V. Moorman,  Marc R. Mansour.

Blood
Volume: 143, Issue: 10, Pages: 933-937.

Frontline and Relapsed Rhabdomyosarcoma (FaR-RMS) Clinical Trial: A Report from the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)

Julia Chisholm,  Henry Mandeville,  Madeleine Adams,  Veronique Minard-Collin,  Timothy Rogers,  Anna Kelsey,  Janet Shipley,  Rick R. van Rijn,  Isabelle de Vries,  Roelof van Ewijk,  Bart de Keizer,  Susanne A. Gatz,  Michela Casanova,  Lisa Lyngsie Hjalgrim,  Charlotte Firth,  Keith Wheatley,  Pamela Kearns,  Wenyu Liu,  Amanda Kirkham,  Helen Rees,  Gianni Bisogno,  Ajla Wasti,  Sara Wakeling,  Delphine Heenen,  Deborah A. Tweddle,  Johannes H. M. Merks,  Meriel Jenney.

Cancers
Volume: 16, Issue: 5, Pages: 998.

Metabolite profiles of medulloblastoma for rapid and non-invasive detection of molecular disease groups

Sarah Kohe,  Christopher Bennett,  Florence Burté,  Magretta Adiamah,  Heather Rose,  Lara Worthington,  Fatma Scerif,  Lesley MacPherson,  Simrandip Gill,  Debbie Hicks,  Edward C. Schwalbe,  Stephen Crosier,  Lisa Storer,  Ambarasu Lourdusamy,  Dipyan Mitra,  Paul S. Morgan,  Robert A. Dineen,  Shivaram Avula,  Barry Pizer,  Martin Wilson,  Nigel Davies,  Daniel Tennant,  Simon Bailey,  Daniel Williamson,  Theodoros N. Arvanitis,  Richard G. Grundy,  Steven C. Clifford,  Andrew C. Peet.

EBioMedicine
Volume: 100, Pages: 104958.

Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression between patients

Alastair Smith,  Nicholas Denny,  Catherine Chahrour,  Kim Sharp,  Natalina Elliot,  Joe Harman,  Thomas Jackson,  Huimin Geng,  Owen Smith,  Jonathan Bond,  Irene Roberts,  Ronald W. Stam,  Nicholas T. Crump,  James O. J. Davies,  Anindita Roy,  Thomas A. Milne.

bioRxiv

Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome

Anna S. Kolodziejczak,  Lea Guerrini-Rousseau,  Julien Masliah Planchon,  Jonas Ecker,  Florian Selt,  Martin Mynarek,  Denise Obrecht,  Martin Sill,  Robert J. Autry,  Eric Stutheit-Zhao,  Steffen Hirsch,  Elsa Amouyal,  Christelle Dufour,  Olivier Ayrault,  Jacob Torrejon,  Sebastian M. Waszak,  Vijay Ramaswamy,  Virve Pentikainen,  Haci Ahmet Demir,  Steven C. Clifford,  Ed C. Schwalbe,  Luca Massimi,  Matija Snuderl,  Kristyn Galbraith,  Matthias A. Karajannis,  Katherine Hill,  Bryan K. Li,  Mike Walsh,  Christine L. White,  Shelagh Redmond,  Loizou Loizos,  Marcus Jakob,  Uwe R. Kordes,  Irene Schmid,  Julia Hauer,  Claudia Blattmann,  Maria Filippidou,  Gianluca Piccolo,  Wolfram Scheurlen,  Ahmed Farrag,  Kerstin Grund,  Christian Sutter,  Torsten Pietsch,  Stephan Frank,  Denis M. Schewe,  David Malkin,  Myriam Ben-Arush,  Astrid Sehested,  Tai-Tong Wong,  Kuo-Sheng Wu,  Yen-Lin Liu,  Fernando Carceller,  Sabine Mueller,  Schuyler Stoller,  Michael D. Taylor,  Uri Tabori,  Eric Bouffet,  Marcel Kool,  Felix Sahm,  Andreas von Deimling,  Andrey Korshunov,  Katja von Hoff,  Christian P. Kratz,  Dominik Sturm,  David T. W. Jones,  Stefan Rutkowski,  Cornelis M. van Tilburg,  Olaf Witt,  Gaëlle Bougeard,  Kristian W. Pajtler,  Stefan M. Pfister,  Franck Bourdeaut,  Till Milde.

Neuro-Oncology
Volume: 25, Issue: 12, Pages: 2273-2286.

Clinical outcome of pediatric medulloblastoma patients with Li–Fraumeni syndrome

Anna S Kolodziejczak,  Lea Guerrini-Rousseau,  Julien Masliah Planchon,  Jonas Ecker,  Florian Selt,  Martin Mynarek,  Denise Obrecht,  Martin Sill,  Robert J Autry,  Eric Stutheit-Zhao,  Steffen Hirsch,  Elsa Amouyal,  Christelle Dufour,  Olivier Ayrault,  Jacob Torrejon,  Sebastian M Waszak,  Vijay Ramaswamy,  Virve Pentikainen,  Haci Ahmet Demir,  Steven C Clifford,  Ed C Schwalbe,  Luca Massimi,  Matija Snuderl,  Kristyn Galbraith,  Matthias A Karajannis,  Katherine Hill,  Bryan K Li,  Mike Walsh,  Christine L White,  Shelagh Redmond,  Loizou Loizos,  Marcus Jakob,  Uwe R Kordes,  Irene Schmid,  Julia Hauer,  Claudia Blattmann,  Maria Filippidou,  Gianluca Piccolo,  Wolfram Scheurlen,  Ahmed Farrag,  Kerstin Grund,  Christian Sutter,  Torsten Pietsch,  Stephan Frank,  Denis M Schewe,  David Malkin,  Myriam Ben-Arush,  Astrid Sehested,  Tai-Tong Wong,  Kuo-Sheng Wu,  Yen-Lin Liu,  Fernando Carceller,  Sabine Mueller,  Schuyler Stoller,  Michael D Taylor,  Uri Tabori,  Eric Bouffet,  Marcel Kool,  Felix Sahm,  Andreas von Deimling,  Andrey Korshunov,  Katja von Hoff,  Christian P Kratz,  Dominik Sturm,  David T W Jones,  Stefan Rutkowski,  Cornelis M van Tilburg,  Olaf Witt,  Gaëlle Bougeard,  Kristian W Pajtler,  Stefan M Pfister,  Franck Bourdeaut,  Till Milde.

Neuro-Oncology
Volume: 25, Issue: 12, Pages: 2273-2286.

Bispecific CAR-iNKT Immunotherapy for High Risk MLL-Rearranged Acute Lymphoblastic Leukemia

Hongwei Ren,  Natalina Elliott,  Bryan Lye,  Joe Cross,  Lucy Field,  Kanagaraju Ponnusamy,  Irene Roberts,  Christina Halsey,  Thomas Arthur Milne,  Anindita Roy,  Anastasios Karadimitris.

Blood
Volume: 142, Issue: Supplement 1, Pages: 766.

Bispecific CAR-iNKT Immunotherapy for High Risk MLL-Rearranged Acute Lymphoblastic Leukemia

Hongwei Ren,  Natalina Elliott,  Bryan Lye,  Joe Cross,  Lucy Field,  Kanagaraju Ponnusamy,  Irene Roberts,  Christina Halsey,  Thomas Arthur Milne,  Anindita Roy,  Anastasios Karadimitris.

Blood
Volume: 142, Issue: Supplement 1, Pages: 766.

Optimizing biomarkers for accurate ependymoma diagnosis, prognostication, and stratification within International Clinical Trials: A BIOMECA study

Rebecca J Chapman,  David R Ghasemi,  Felipe Andreiuolo,  Valentina Zschernack,  Arnault Tauziede Espariat,  Francesca R Buttarelli,  Felice Giangaspero,  Jacques Grill,  Christine Haberler,  Simon M L Paine,  Ian Scott,  Thomas S Jacques,  Martin Sill,  Stefan Pfister,  John-Paul Kilday,  Pierre Leblond,  Maura Massimino,  Hendrik Witt,  Piergiorgio Modena,  Pascale Varlet,  Torsten Pietsch,  Richard G Grundy,  Kristian W Pajtler,  Timothy A Ritzmann.

Neuro-Oncology
Volume: 25, Issue: 10, Pages: 1871-1882.

Targeting oncogenic microRNAs from the miR-371~373 and miR-302/367 clusters in malignant germ cell tumours causes growth inhibition through cell cycle disruption

Shivani Bailey,  Marta Ferraresso,  Luz Alonso-Crisostomo,  Dawn Ward,  Stephen Smith,  James C. Nicholson,  Harpreet Saini,  Anton J. Enright,  Cinzia G. Scarpini,  Nicholas Coleman,  Matthew J. Murray.

British Journal of Cancer
Volume: 129, Issue: 9, Pages: 1451-1461.

Optimizing biomarkers for accurate ependymoma diagnosis, prognostication, and stratification within International Clinical Trials: A BIOMECA study

Rebecca J Chapman,  David R Ghasemi,  Felipe Andreiuolo,  Valentina Zschernack,  Arnault Tauziede Espariat,  Francesca R Buttarelli,  Felice Giangaspero,  Jacques Grill,  Christine Haberler,  Simon M L Paine,  Ian Scott,  Thomas S Jacques,  Martin Sill.

Neuro-Oncology
Volume: 25, Issue: 10, Pages: 1871-1882.

MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia

Nicholas T. Crump,  Alastair L. Smith,  Laura Godfrey,  Ana M. Dopico-Fernandez,  Nicholas Denny,  Joe R. Harman,  Joseph C. Hamley,  Nicole E. Jackson,  Catherine Chahrour,  Simone Riva,  Siobhan Rice,  Jaehoon Kim,  Venkatesha Basrur,  Damian Fermin,  Kojo Elenitoba-Johnson,  Robert G. Roeder,  C. David Allis,  Irene Roberts,  Anindita Roy,  Huimin Geng,  James O. J. Davies,  Thomas A. Milne.

Nature Communications
Volume: 14, Issue: 1, Pages: 5208.

The genomic landscape of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Qingsong Gao,  Sarra L. Ryan,  Ilaria Iacobucci,  Pankaj S. Ghate,  Ruth E. Cranston,  Claire Schwab,  Abdelrahman H. Elsayed,  Lei Shi,  Stanley Pounds,  Shaohua Lei,  Pradyuamna Baviskar,  Deqing Pei,  Cheng Cheng,  Matthew Bashton,  Paul Sinclair,  David R. Bentley,  Mark T. Ross,  Zoya Kingsbury,  Terena James,  Kathryn G. Roberts,  Meenakshi Devidas,  Yiping Fan,  Wenan Chen,  Ti-Cheng Chang,  Gang Wu,  Andrew Carroll,  Nyla Heerema,  Virginia Valentine,  Marcus Valentine,  Wenjian Yang,  Jun J. Yang,  Anthony V. Moorman,  Christine J. Harrison,  Charles G. Mullighan.

Blood
Volume: 142, Issue: 8, Pages: 711-723.

Retinal pigment epithelium exhibits gene expression and phagocytic activity alterations when exposed to retinoblastoma chemotherapeutics

Rodrigo Cerna-Chavez,  Agata Rozanska,  Giulia Lodovica Poretti,  Nissim Benvenisty,  Manoj Parulekar,  Majlinda Lako.

Experimental Eye Research
Volume: 233, Pages: 109542.

Retinal pigment epithelium exhibits gene expression and phagocytic activity alterations when exposed to retinoblastoma chemotherapeutics

Rodrigo Cerna-Chavez,  Agata Rozanska,  Giulia Lodovica Poretti,  Nissim Benvenisty,  Manoj Parulekar,  Majlinda Lako.

Experimental Eye Research
Volume: 233, Pages: 109542.

P332: LIN28B: AN IMPORTANT ONCO-FETAL GENE IN INFANT ACUTE LYMPHOBLASTIC LEUKAEMIA

Rebecca Ling,  Thomas Jackson,  Natalina Elliott,  Joe Cross,  Siobhan Rice,  Rebecca Howitt,  Alastair Smith,  Joe Harman,  Nicholas T Crump,  Guanlin Wang,  Deena Iskander,  Supat Thongjuea,  Philip Ancliff,  Beth Psaila,  Irene Roberts,  Thomas Milne,  Anindita Roy.

HemaSphere
Volume: 7, Issue: S3, Pages: e5649016.

The Clinicogenomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia

David O'Connor,  Jonas Demeulemeester,  Lucia Conde,  Amy Kirkwood,  Kent Fung,  Foteini Papaleonidopoulou,  Gianna Bloye,  Nadine Farah,  Sunniyat Rahman,  Jeremy Hancock,  Caroline Bateman,  Sarah Inglott,  Jon Mee,  Javier Herrero,  Peter Van Loo,  Anthony V. Moorman,  Ajay Vora,  Marc R. Mansour.

Journal of Clinical Oncology
Volume: 41, Issue: 19, Pages: 3545-3556.

The proteomic landscape of soft tissue sarcomas

Jessica Burns,  Christopher P. Wilding,  Lukas Krasny,  Xixuan Zhu,  Madhumeeta Chadha,  Yuen Bun Tam,  Hari Ps,  Aswanth H. Mahalingam,  Alexander T. J. Lee,  Amani Arthur,  Nafia Guljar,  Emma Perkins,  Valeriya Pankova,  Andrew Jenks,  Vanessa Djabatey,  Cornelia Szecsei,  Frank McCarthy,  Chanthirika Ragulan,  Martina Milighetti,  Theodoros I. Roumeliotis,  Stephen Crosier,  Martina Finetti,  Jyoti S. Choudhary,  Ian Judson,  Cyril Fisher,  Eugene F. Schuster,  Anguraj Sadanandam,  Tom W. Chen,  Daniel Williamson,  Khin Thway,  Robin L. Jones,  Maggie C. U. Cheang,  Paul H. Huang.

Nature Communications
Volume: 14, Issue: 1, Pages: 3834.

The proteomic landscape of soft tissue sarcomas

Jessica Burns,  Christopher P. Wilding,  Lukas Krasny,  Xixuan Zhu,  Madhumeeta Chadha,  Yuen Bun Tam,  Hari Ps,  Aswanth H. Mahalingam,  Alexander T. J. Lee,  Amani Arthur,  Nafia Guljar,  Emma Perkins,  Valeriya Pankova,  Andrew Jenks,  Vanessa Djabatey,  Cornelia Szecsei,  Frank McCarthy,  Chanthirika Ragulan,  Martina Milighetti,  Theodoros I. Roumeliotis,  Stephen Crosier,  Martina Finetti,  Jyoti S. Choudhary,  Ian Judson,  Cyril Fisher,  Eugene F. Schuster,  Anguraj Sadanandam,  Tom W. Chen,  Daniel Williamson,  Khin Thway,  Robin L. Jones,  Maggie C. U. Cheang,  Paul H. Huang.

Nature Communications
Volume: 14, Issue: 1, Pages: 3834.

Clinical outcome of pediatric medulloblastoma patients with Li–Fraumeni syndrome

Anna S Kolodziejczak,  Lea Guerrini-Rousseau,  Julien Masliah Planchon,  Jonas Ecker,  Florian Selt,  Martin Mynarek,  Denise Obrecht,  Martin Sill,  Robert J Autry,  Eric Stutheit-Zhao,  Steffen Hirsch,  Elsa Amouyal,  Christelle Dufour,  Olivier Ayrault,  Jacob Torrejon,  Sebastian M Waszak,  Vijay Ramaswamy,  Virve Pentikainen,  Haci Ahmet Demir,  Steven C Clifford,  Ed C Schwalbe,  Luca Massimi,  Matija Snuderl,  Kristyn Galbraith,  Matthias A Karajannis,  Katherine Hill,  Bryan K Li,  Mike Walsh,  Christine L White,  Shelagh Redmond,  Loizou Loizos,  Marcus Jakob,  Uwe R Kordes,  Irene Schmid,  Julia Hauer,  Claudia Blattmann,  Maria Filippidou,  Gianluca Piccolo,  Wolfram Scheurlen,  Ahmed Farrag,  Kerstin Grund,  Christian Sutter,  Torsten Pietsch,  Stephan Frank,  Denis M Schewe,  David Malkin,  Myriam Ben-Arush,  Astrid Sehested,  Tai-Tong Wong,  Kuo-Sheng Wu,  Yen-Lin Liu,  Fernando Carceller,  Sabine Mueller,  Schuyler Stoller,  Michael D Taylor,  Uri Tabori,  Eric Bouffet,  Marcel Kool,  Felix Sahm,  Andreas von Deimling,  Andrey Korshunov,  Katja von Hoff,  Christian P Kratz,  Dominik Sturm,  David T W Jones,  Stefan Rutkowski,  Cornelis M van Tilburg,  Olaf Witt,  Gaëlle Bougeard,  Kristian W Pajtler,  Stefan M Pfister,  Franck Bourdeaut,  Till Milde.

Neuro-Oncology
Pages: noad114.

Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification

Jack Goddard,  Jemma Castle,  Emily Southworth,  Anya Fletcher,  Stephen Crosier,  Idoia Martin-Guerrero,  Miguel García-Ariza,  Aurora Navajas,  Julien Masliah-Planchon,  Franck Bourdeaut,  Christelle Dufour,  Olivier Ayrault,  Tobias Goschzik,  Torsten Pietsch,  Martin Sill,  Stefan M. Pfister,  Stefan Rutkowski,  Stacey Richardson,  Rebecca M. Hill,  Daniel Williamson,  Simon Bailey,  Edward C. Schwalbe,  Steven C. Clifford,  Debbie Hicks.

Acta Neuropathologica
Volume: 145, Issue: 5, Pages: 651-666.

Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification

Jack Goddard,  Jemma Castle,  Emily Southworth,  Anya Fletcher,  Stephen Crosier,  Idoia Martin-Guerrero,  Miguel García-Ariza,  Aurora Navajas,  Julien Masliah-Planchon,  Franck Bourdeaut,  Christelle Dufour,  Olivier Ayrault,  Tobias Goschzik,  Torsten Pietsch,  Martin Sill,  Stefan M. Pfister,  Stefan Rutkowski,  Stacey Richardson,  Rebecca M. Hill,  Daniel Williamson,  Simon Bailey,  Edward C. Schwalbe,  Steven C. Clifford,  Debbie Hicks.

Acta Neuropathologica
Volume: 145, Issue: 5, Pages: 651-666.

Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation–Sparing Approaches: An International Cohort Study

Craig Erker,  Martin Mynarek,  Simon Bailey,  Claire M. Mazewski,  Lorena Baroni,  Maura Massimino,  Juliette Hukin,  Dolly Aguilera,  Andrea M. Cappellano,  Vijay Ramaswamy,  Alvaro Lassaletta,  Sébastien Perreault,  Cassie N. Kline,  Revathi Rajagopal,  George Michaiel,  Michal Zapotocky,  Vicente Santa-Maria Lopez,  Andres Morales La Madrid,  Chantel Cacciotti,  Eric S. Sandler,  Lindsey M. Hoffman,  Darren Klawinski,  Sara Khan,  Ralph Salloum,  Anna L. Hoppmann,  Valérie Larouche,  Kathleen Dorris,  Helen Toledano,  Stephen W. Gilheeney,  Mohamed S. Abdelbaki,  Beverly Wilson,  Derek S. Tsang,  Jeffrey Knipstein,  Michal Yalon Oren,  Shafqat Shah,  Jeffrey C. Murray,  Kevin F. Ginn,  Zhihong J. Wang,  Gudrun Fleischhack,  Denise Obrecht,  Svenja Tonn,  Virginia L. Harrod,  Kara Matheson,  Bruce Crooks,  Douglas R. Strother,  Kenneth J. Cohen,  Jordan R. Hansford,  Sabine Mueller,  Ashley Margol,  Amar Gajjar,  Girish Dhall,  Jonathan L. Finlay,  Paul A. Northcott,  Stefan Rutkowski,  Steven C. Clifford,  Giles Robinson,  Eric Bouffet,  Lucie Lafay-Cousin.

Journal of Clinical Oncology
Volume: 41, Issue: 10, Pages: 1921-1932.

Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation–Sparing Approaches: An International Cohort Study

Craig Erker,  Martin Mynarek,  Simon Bailey,  Claire M. Mazewski,  Lorena Baroni,  Maura Massimino,  Juliette Hukin,  Dolly Aguilera,  Andrea M. Cappellano,  Vijay Ramaswamy,  Alvaro Lassaletta,  Sébastien Perreault,  Cassie N. Kline,  Revathi Rajagopal,  George Michaiel,  Michal Zapotocky,  Vicente Santa-Maria Lopez,  Andres Morales La Madrid,  Chantel Cacciotti,  Eric S. Sandler,  Lindsey M. Hoffman,  Darren Klawinski,  Sara Khan,  Ralph Salloum,  Anna L. Hoppmann,  Valérie Larouche,  Kathleen Dorris,  Helen Toledano,  Stephen W. Gilheeney,  Mohamed S. Abdelbaki,  Beverly Wilson,  Derek S. Tsang,  Jeffrey Knipstein,  Michal Yalon Oren,  Shafqat Shah,  Jeffrey C. Murray,  Kevin F. Ginn,  Zhihong J. Wang,  Gudrun Fleischhack,  Denise Obrecht,  Svenja Tonn,  Virginia L. Harrod,  Kara Matheson,  Bruce Crooks,  Douglas R. Strother,  Kenneth J. Cohen,  Jordan R. Hansford,  Sabine Mueller,  Ashley Margol,  Amar Gajjar,  Girish Dhall,  Jonathan L. Finlay,  Paul A. Northcott,  Stefan Rutkowski,  Steven C. Clifford,  Giles Robinson,  Eric Bouffet,  Lucie Lafay-Cousin.

Journal of Clinical Oncology
Volume: 41, Issue: 10, Pages: 1921-1932.

Whole genome sequencing provides comprehensive genetic testing in childhood B-cell acute lymphoblastic leukaemia

Sarra L. Ryan,  John F. Peden,  Zoya Kingsbury,  Claire J. Schwab,  Terena James,  Petri Polonen,  Martina Mijuskovic,  Jenn Becq,  Richard Yim,  Ruth E. Cranston,  Dale J. Hedges,  Kathryn G. Roberts,  Charles G. Mullighan,  Ajay Vora,  Lisa J. Russell,  Robert Bain,  Anthony V. Moorman,  David R. Bentley,  Christine J. Harrison,  Mark T. Ross.

Leukemia
Volume: 37, Issue: 3, Pages: 518-528.

Disruption to the FOXO-PRDM1 axis resulting from deletions of chromosome 6 in acute lymphoblastic leukaemia

Paul B. Sinclair,  Ruth E. Cranston,  Prahlad Raninga,  Joanna Cheng,  Rebecca Hanna,  Zoe Hawking,  Steven Hair,  Sarra L. Ryan,  Amir Enshaei,  Sirintra Nakjang,  Vikki Rand,  Helen J. Blair,  Anthony V. Moorman,  Olaf Heidenreich,  Christine J. Harrison.

Leukemia
Volume: 37, Issue: 3, Pages: 636-649.

Integrative genomic analysis of childhood acute lymphoblastic leukaemia lacking a genetic biomarker in the UKALL2003 clinical trial

Claire Schwab,  Ruth E. Cranston,  Sarra L. Ryan,  Ellie Butler,  Emily Winterman,  Zoe Hawking,  Matthew Bashton,  Amir Enshaei,  Lisa J. Russell,  Zoya Kingsbury,  John F. Peden,  Emilio Barretta,  James Murray,  Jude Gibson,  Andrew C. Hinchliffe,  Robert Bain,  Ajay Vora,  David R. Bentley,  Mark T. Ross,  Anthony V. Moorman,  Christine J. Harrison.

Leukemia
Volume: 37, Issue: 3, Pages: 529-538.

A microRNA expression signature in infant t(4;11) MLL-AF4+ BCP-ALL uncovers novel therapeutic targets

Camille Malouf,  Alasdair Duguid,  Giuseppina Camiolo,  Leslie Nitsche,  Hélène Jakobczyk,  Rishi S. Kotecha,  Richard A. Anderson,  Neil A. Barrett,  Owen P. Smith,  Katrin Ottersbach.

Use of Optical Genome Mapping to Detect Structural Variants in Neuroblastoma

Ruby G. Barford,  Emily Whittle,  Laura Weir,  Fang Chyi Fong,  Angharad Goodman,  Hannah E. Hartley,  Lisa M. Allinson,  Deborah A. Tweddle.

Cancers
Volume: 15, Issue: 21, Pages: 5233.

Clinical characteristics and outcomes of B-cell precursor ALL with MEF2D rearrangements: a retrospective study by the Ponte di Legno Childhood ALL Working Group

Kentaro Ohki,  Ellie R. Butler,  Nobutaka Kiyokawa,  Shinsuke Hirabayashi,  Anke K. Bergmann,  Anja Möricke,  Judith M. Boer,  Hélène Cavé,  Giovanni Cazzaniga,  Allen Eng Juh Yeoh,  Masashi Sanada,  Toshihiko Imamura,  Hiroto Inaba,  Charles G. Mullighan,  Mignon L. Loh,  Ulrika Norén-Nyström,  Lee-Yung Shih,  Marketa Zaliova,  Ching-Hon Pui,  Oskar A. Haas,  Christine J. Harrison,  Anthony V. Moorman,  Atsushi Manabe.

Leukemia
Volume: 37, Issue: 1, Pages: 212-216.

Use of Optical Genome Mapping to Detect Structural Variants in Neuroblastoma

Ruby G. Barford,  Emily Whittle,  Laura Weir,  Fang Chyi Fong,  Angharad Goodman,  Hannah E. Hartley,  Lisa M. Allinson,  Deborah A. Tweddle.

Cancers
Volume: 15, Issue: 21, Pages: 5233.

Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement

Simon Bomken,  Amir Enshaei,  Edward C. Schwalbe,  Aneta Mikulasova,  Yunfeng Dai,  Masood Zaka,  Kent T. M. Fung,  Matthew Bashton,  Huezin Lim,  Lisa Jones,  Nefeli Karataraki,  Emily Winterman,  Cody Ashby,  Andishe Attarbaschi,  Yves Bertrand,  Jutta Bradtke,  Barbara Buldini,  G. A. Amos Burke,  Giovanni Cazzaniga,  Gudrun Gohring,  Hesta A. de Groot-Kruseman,  Claudia Haferlach,  Luca Lo Nigro,  Mayur Parihar,  Adriana Plesa,  Emma Seaford,  Edwin Sonneveld,  Sabine Strehl,  Vincent H. J. van der Velden,  Vikki Rand,  Stephen P. Hunger,  Christine J. Harrison,  Chris M. Bacon,  Frederik W. van Delft,  Mignon L. Loh,  John Moppett,  Josef Vormoor,  Brian A. Walker,  Anthony V. Moorman,  Lisa J. Russell.

Haematologica
Volume: 108, Issue: 3, Pages: 717-731.

DNA methylation-based classification of glioneuronal tumours synergises with histology and radiology to refine accurate molecular stratification

Thomas J. Stone,  Kshitij Mankad,  Ai Peng Tan,  Wajanat Jan,  Jessica C. Pickles,  Maria Gogou,  Jane Chalker,  Iwona Slodkowska,  Emily Pang,  Mark Kristiansen,  Gaganjit K. Madhan,  Leysa Forrest,  Deborah Hughes,  Eleni Koutroumanidou,  Talisa Mistry,  Olumide Ogunbiyi,  Saira W. Ahmed,  J. Helen Cross,  Mike Hubank,  Darren Hargrave,  Thomas S. Jacques.

Neuropathology and Applied Neurobiology
Volume: 49, Issue: 2, Pages: e12894.

Timing is everything: A connection between medulloblastoma prognosis and foetal cerebellar development

Daniel Williamson,  Edward C. Schwalbe,  Simon Bailey,  Steven C. Clifford.

Neuropathology and Applied Neurobiology
Volume: 49, Issue: 3, Pages: e12903.

Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement

Simon Bomken,  Amir Enshaei,  Edward C. Schwalbe,  Aneta Mikulasova,  Yunfeng Dai,  Masood Zaka,  Kent T. M. Fung,  Matthew Bashton,  Huezin Lim,  Lisa Jones,  Nefeli Karataraki,  Emily Winterman,  Cody Ashby,  Andishe Attarbaschi,  Yves Bertrand,  Jutta Bradtke,  Barbara Buldini,  G. A. Amos Burke,  Giovanni Cazzaniga,  Gudrun Gohring,  Hesta A. de Groot-Kruseman,  Claudia Haferlach,  Luca Lo Nigro,  Mayur Parihar,  Adriana Plesa,  Emma Seaford,  Edwin Sonneveld,  Sabine Strehl,  Vincent H. J. van der Velden,  Vikki Rand,  Stephen P. Hunger,  Christine J. Harrison,  Chris M. Bacon,  Frederik W. van Delft,  Mignon L. Loh,  John Moppett,  Josef Vormoor,  Brian A. Walker,  Anthony V. Moorman,  Lisa J. Russell.

Haematologica
Volume: 108, Issue: 3, Pages: 717-731.

DNA methylation-based classification of glioneuronal tumours synergises with histology and radiology to refine accurate molecular stratification

Thomas J. Stone,  Kshitij Mankad,  Ai Peng Tan,  Wajanat Jan,  Jessica C. Pickles,  Maria Gogou,  Jane Chalker,  Iwona Slodkowska,  Emily Pang,  Mark Kristiansen,  Gaganjit K. Madhan,  Leysa Forrest,  Deborah Hughes,  Eleni Koutroumanidou,  Talisa Mistry,  Olumide Ogunbiyi,  Saira W. Ahmed,  J. Helen Cross,  Mike Hubank,  Darren Hargrave,  Thomas S. Jacques.

Neuropathology and Applied Neurobiology
Volume: 49, Issue: 2, Pages: e12894.

Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement

Simon Bomken,  Amir Enshaei,  Edward C. Schwalbe,  Aneta Mikulasova,  Yunfeng Dai,  Masood Zaka,  Kent T. M. Fung,  Matthew Bashton,  Huezin Lim,  Lisa Jones,  Nefeli Karataraki,  Emily Winterman,  Cody Ashby,  Andishe Attarbaschi,  Yves Bertrand,  Jutta Bradtke,  Barbara Buldini,  G. A. Amos Burke,  Giovanni Cazzaniga,  Gudrun Gohring,  Hesta A. de Groot-Kruseman,  Claudia Haferlach,  Luca Lo Nigro,  Mayur Parihar,  Adriana Plesa,  Emma Seaford,  Edwin Sonneveld,  Sabine Strehl,  Vincent H. J. van der Velden,  Vikki Rand,  Stephen P. Hunger,  Christine J. Harrison,  Chris M. Bacon,  Frederik W. van Delft,  Mignon L. Loh,  John Moppett,  Josef Vormoor,  Brian A. Walker,  Anthony V. Moorman,  Lisa J. Russell.

Haematologica
Volume: 108, Issue: 3, Pages: 717-731.

Timing is everything: A connection between medulloblastoma prognosis and foetal cerebellar development

Daniel Williamson,  Edward C. Schwalbe,  Simon Bailey,  Steven C. Clifford.

Neuropathology and Applied Neurobiology
Volume: 49, Issue: 3, Pages: e12903.

Human bone marrow organoids for disease modelling, discovery and validation of therapeutic targets in hematological malignancies

Abdullah O. Khan,  Antonio Rodriguez-Romera,  Jasmeet S. Reyat,  Aude-Anais Olijnik,  Michela Colombo,  Guanlin Wang,  Wei Xiong Wen,  Nikolaos Sousos,  Lauren C. Murphy,  Beata Grygielska,  Gina Perrella,  Christopher B. Mahony,  Rebecca E. Ling,  Natalina E. Elliott,  Christina Simoglou Karali,  Andrew P. Stone,  Samuel Kemble,  Emily A. Cutler,  Adele K. Fielding,  Adam P. Croft,  David Bassett,  Gowsihan Poologasundarampillai,  Anindita Roy,  Sarah Gooding,  Julie Rayes,  Kellie R. Machlus,  Bethan Psaila.

Cancer Discovery
Pages: CD-22-0199.

Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation

Zhuoyao Chen,  Rafael M. Ioris,  Stacey Richardson,  Ava N. Van Ess,  Iolanda Vendrell,  Benedikt M. Kessler,  Francesca M. Buffa,  Luca Busino,  Steven C. Clifford,  Alex N. Bullock,  Vincenzo D’Angiolella.

Cell Death & Differentiation
Volume: 29, Issue: 10, Pages: 1955-1969.

LGR5 targeting molecules as therapeutic agents for multiple cancer types

Hung-Chang Chen,  Nico Mueller,  Katherine Stott,  Eilidh Rivers,  Chrysa Kapeni,  Carolin M. Sauer,  Flavio Beke,  Stephen Walsh,  Nicola Ashman,  Louise O’Brien,  Amir Rafati Fard,  Arman Godsinia,  Fadwa Joud,  Olivier Giger,  Inti Zlobec,  Ioana Olan,  Sarah J. Aitken,  Matthew Hoare,  Richard Mair,  Eva Serrao,  James D. Brenton,  Alicia Garcia-Gimenez,  Simon E. Richardson,  Brian Huntly,  David R. Spring,  Mikkel-Ole Skjødt,  Karsten Skjødt,  Marc de la Roche,  Maike de la Roche.

LGR5 targeting molecules as therapeutic agents for multiple cancer types

Hung-Chang Chen,  Nico Mueller,  Katherine Stott,  Eilidh Rivers,  Chrysa Kapeni,  Carolin M. Sauer,  Flavio Beke,  Stephen Walsh,  Nicola Ashman,  Louise O’Brien,  Amir Rafati Fard,  Arman Godsinia,  Fadwa Joud,  Olivier Giger,  Inti Zlobec,  Ioana Olan,  Sarah J. Aitken,  Matthew Hoare,  Richard Mair,  Eva Serrao,  James D. Brenton,  Alicia Garcia-Gimenez,  Simon E. Richardson,  Brian Huntly,  David R. Spring,  Mikkel-Ole Skjødt,  Karsten Skjødt,  Marc de la Roche,  Maike de la Roche.

Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development

Marina Danilenko,  Masood Zaka,  Claire Keeling,  Stephen Crosier,  Stephanie Lyman,  Martina Finetti,  Daniel Williamson,  Rafiqul Hussain,  Jonathan Coxhead,  Peixun Zhou,  Rebecca M. Hill,  Debbie Hicks,  Vikki Rand,  Abhijit Joshi,  Edward C. Schwalbe,  Simon Bailey,  Steven C. Clifford.

Acta Neuropathologica
Volume: 144, Issue: 3, Pages: 565-578.

Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development

Marina Danilenko,  Masood Zaka,  Claire Keeling,  Stephen Crosier,  Stephanie Lyman,  Martina Finetti,  Daniel Williamson,  Rafiqul Hussain,  Jonathan Coxhead,  Peixun Zhou,  Rebecca M. Hill,  Debbie Hicks,  Vikki Rand,  Abhijit Joshi,  Edward C. Schwalbe,  Simon Bailey,  Steven C. Clifford.

Acta Neuropathologica
Volume: 144, Issue: 3, Pages: 565-578.

Clonal diversification and histogenesis of malignant germ cell tumours

Thomas R. W. Oliver,  Lia Chappell,  Rashesh Sanghvi,  Lauren Deighton,  Naser Ansari-Pour,  Stefan C. Dentro,  Matthew D. Young,  Tim H. H. Coorens,  Hyunchul Jung,  Tim Butler,  Matthew D. C. Neville,  Daniel Leongamornlert,  Mathijs A. Sanders,  Yvette Hooks,  Alex Cagan,  Thomas J. Mitchell,  Isidro Cortes-Ciriano,  Anne Y. Warren,  David C. Wedge,  Rakesh Heer,  Nicholas Coleman,  Matthew J. Murray,  Peter J. Campbell,  Raheleh Rahbari,  Sam Behjati.

Nature Communications
Volume: 13, Issue: 1, Pages: 4272.

Clonal diversification and histogenesis of malignant germ cell tumours

Thomas R. W. Oliver,  Lia Chappell,  Rashesh Sanghvi,  Lauren Deighton,  Naser Ansari-Pour,  Stefan C. Dentro,  Matthew D. Young,  Tim H. H. Coorens,  Hyunchul Jung,  Tim Butler,  Matthew D. C. Neville,  Daniel Leongamornlert,  Mathijs A. Sanders,  Yvette Hooks,  Alex Cagan,  Thomas J. Mitchell,  Isidro Cortes-Ciriano,  Anne Y. Warren,  David C. Wedge,  Rakesh Heer,  Nicholas Coleman,  Matthew J. Murray,  Peter J. Campbell,  Raheleh Rahbari,  Sam Behjati.

Nature Communications
Volume: 13, Issue: 1, Pages: 4272.

Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development

Daniel Williamson,  Edward C. Schwalbe,  Debbie Hicks,  Kimberly A. Aldinger,  Janet C. Lindsey,  Stephen Crosier,  Stacey Richardson,  Jack Goddard,  Rebecca M. Hill,  Jemma Castle,  Yura Grabovska,  James Hacking,  Barry Pizer,  Stephen B. Wharton,  Thomas S. Jacques,  Abhijit Joshi,  Simon Bailey,  Steven C. Clifford.

Cell Reports
Volume: 40, Issue: 5, Pages: 111162.

Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development

Daniel Williamson,  Edward C. Schwalbe,  Debbie Hicks,  Kimberly A. Aldinger,  Janet C. Lindsey,  Stephen Crosier,  Stacey Richardson,  Jack Goddard,  Rebecca M. Hill,  Jemma Castle,  Yura Grabovska,  James Hacking,  Barry Pizer,  Stephen B. Wharton,  Thomas S. Jacques,  Abhijit Joshi,  Simon Bailey,  Steven C. Clifford.

Cell Reports
Volume: 40, Issue: 5, Pages: 111162.

Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia

Paul M. Maciocia,  Patrycja A. Wawrzyniecka,  Nicola C. Maciocia,  Amy Burley,  Thaneswari Karpanasamy,  Sam Devereaux,  Malika Hoekx,  David O’Connor,  Theresa Leon,  Tanya Rapoz-D’Silva,  Rachael Pocock,  Sunniyat Rahman,  Giuseppe Gritti,  Diana C. Yánez,  Susan Ross,  Tessa Crompton,  Owen Williams,  Lydia Lee,  Martin A. Pule,  Marc R. Mansour.

Blood
Volume: 140, Issue: 1, Pages: 25-37.

PAF1 and FACT cooperate with MLL-AF4 to drive enhancer activity in leukemia

Nicholas T. Crump,  Alastair Smith,  Laura Godfrey,  Nicole Jackson,  Siobhan Rice,  Jaehoon Kim,  Venkatesha Basrur,  Damian Fermin,  Kojo Elenitoba-Johnson,  Robert G. Roeder,  C. David Allis,  Irene Roberts,  Anindita Roy,  Thomas A. Milne.

PAF1 and FACT cooperate with MLL-AF4 to drive enhancer activity in leukemia

Nicholas T. Crump,  Alastair Smith,  Laura Godfrey,  Nicole Jackson,  Siobhan Rice,  Jaehoon Kim,  Venkatesha Basrur,  Damian Fermin,  Kojo Elenitoba-Johnson,  Robert G. Roeder,  C. David Allis,  Irene Roberts,  Anindita Roy,  Thomas A. Milne.

pRB-Depleted Pluripotent Stem Cell Retinal Organoids Recapitulate Cell State Transitions of Retinoblastoma Development and Suggest an Important Role for pRB in Retinal Cell Differentiation

Agata Rozanska,  Rodrigo Cerna-Chavez,  Rachel Queen,  Joseph Collin,  Darin Zerti,  Birthe Dorgau,  Chia Shyan Beh,  Tracey Davey,  Jonathan Coxhead,  Rafiqul Hussain,  Jumana Al-Aama,  David H Steel,  Nissim Benvenisty,  Lyle Armstrong,  Manoj Parulekar,  Majlinda Lako.

Stem Cells Translational Medicine
Volume: 11, Issue: 4, Pages: 415-433.

pRB-Depleted Pluripotent Stem Cell Retinal Organoids Recapitulate Cell State Transitions of Retinoblastoma Development and Suggest an Important Role for pRB in Retinal Cell Differentiation

Agata Rozanska,  Rodrigo Cerna-Chavez,  Rachel Queen,  Joseph Collin,  Darin Zerti,  Birthe Dorgau,  Chia Shyan Beh,  Tracey Davey,  Jonathan Coxhead,  Rafiqul Hussain,  Jumana Al-Aama,  David H Steel,  Nissim Benvenisty,  Lyle Armstrong,  Manoj Parulekar,  Majlinda Lako.

Stem Cells Translational Medicine
Volume: 11, Issue: 4, Pages: 415-433.

Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma

Alexander M. Newman,  Masood Zaka,  Peixun Zhou,  Alex E. Blain,  Amy Erhorn,  Amy Barnard,  Rachel E. Crossland,  Sarah Wilkinson,  Amir Enshaei,  Julian De Zordi,  Fiona Harding,  Mary Taj,  Katrina M. Wood,  Despina Televantou,  Suzanne D. Turner,  G. A. Amos Burke,  Christine J. Harrison,  Simon Bomken,  Chris M. Bacon,  Vikki Rand.

Leukemia
Volume: 36, Issue: 3, Pages: 781-789.

Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma

Alexander M. Newman,  Masood Zaka,  Peixun Zhou,  Alex E. Blain,  Amy Erhorn,  Amy Barnard,  Rachel E. Crossland,  Sarah Wilkinson,  Amir Enshaei,  Julian De Zordi,  Fiona Harding,  Mary Taj,  Katrina M. Wood,  Despina Televantou,  Suzanne D. Turner,  G. A. Amos Burke,  Christine J. Harrison,  Simon Bomken,  Chris M. Bacon,  Vikki Rand.

Leukemia
Volume: 36, Issue: 3, Pages: 781-789.

Genetic characterisation of childhood B-other-acute lymphoblastic leukaemia in UK patients by fluorescence in situ hybridisation and Multiplex Ligation-dependent Probe Amplification

Claire J. Schwab,  Daniel Murdy,  Ellie Butler,  Amir Enshaei,  Emily Winterman,  Ruth E. Cranston,  Sarra Ryan,  Emilio Barretta,  Zoe Hawking,  James Murray,  Grace Antony,  Ajay Vora,  Anthony V. Moorman,  Christine J. Harrison.

British Journal of Haematology
Volume: 196, Issue: 3, Pages: 753-763.

DNA-thioguanine concentration and relapse risk in children and young adults with acute lymphoblastic leukemia: an IPD meta-analysis

Linea N. Toksvang,  Kathrine Grell,  Jacob Nersting,  Matilda Degn,  Stine N. Nielsen,  Jonas Abrahamsson,  Bendik Lund,  Jukka Kanerva,  Ólafur G. Jónsson,  Kristi Lepik,  Goda Vaitkeviciene,  Laimonas Griškevicius,  Petter Quist-Paulsen,  Ajay Vora,  Anthony V. Moorman,  Daniel Murdy,  Martin Zimmermann,  Anja Möricke,  Bruce Bostrom,  Jaitri Joshi,  Lisa L. Hjalgrim,  Kim P. Dalhoff,  Bodil Als-Nielsen,  Kjeld Schmiegelow.

Leukemia
Volume: 36, Issue: 1, Pages: 33-41.

Loss of ALK hotspot mutations in relapsed neuroblastoma

Lisa M. Allinson,  Aaron Potts,  Angharad Goodman,  Nick Bown,  Matthew Bashton,  Dean Thompson,  Nermine O. Basta,  Alem S. Gabriel,  Michael McCorkindale,  Antony Ng,  Richard J. Q. McNally,  Deborah A. Tweddle.

Genes, Chromosomes and Cancer
Volume: 61, Issue: 12, Pages: 747-753.

Molecular characterisation and clinical outcome of B-cell precursor acute lymphoblastic leukaemia with IG-MYC rearrangement

Simon Bomken,  Amir Enshaei,  Edward C. Schwalbe,  Aneta Mikulasova,  Yunfeng Dai,  Masood Zaka,  Kent T. M. Fung,  Matthew Bashton,  Huezin Lim,  Lisa Jones,  Nefeli Karataraki,  Emily Winterman,  Cody Ashby,  Andishe Attarbaschi,  Yves Bertrand,  Jutta Bradtke,  Barbara Buldini,  G. A. Amos Burke,  Giovanni Cazzaniga,  Gudrun Gohring,  Hesta A. de Groot-Kruseman,  Claudia Haferlach,  Luca Lo Nigro,  Mayur Parihar,  Adriana Plesa,  Emma Seaford,  Edwin Sonneveld,  Sabine Strehl,  Vincent H. J. van der Velden,  Vikki Rand,  Stephen P. Hunger,  Christine J. Harrison,  Chris M. Bacon,  Frederik W. van Delft,  Mignon L. Loh,  John Moppett,  Josef Vormoor,  Brian A. Walker,  Anthony V. Moorman,  Lisa J. Russell.

Haematologica

Loss of ALK hotspot mutations in relapsed neuroblastoma

Lisa M. Allinson,  Aaron Potts,  Angharad Goodman,  Nick Bown,  Matthew Bashton,  Dean Thompson,  Nermine O. Basta,  Alem S. Gabriel,  Michael McCorkindale,  Antony Ng,  Richard J. Q. McNally,  Deborah A. Tweddle.

Genes, Chromosomes and Cancer
Volume: 61, Issue: 12, Pages: 747-753.

A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program

Siobhan Rice,  Thomas Jackson,  Nicholas T. Crump,  Nicholas Fordham,  Natalina Elliott,  Sorcha O’Byrne,  Maria del Mar Lara Fanego,  Dilys Addy,  Trisevgeni Crabb,  Carryl Dryden,  Sarah Inglott,  Dariusz Ladon,  Gary Wright,  Jack Bartram,  Philip Ancliff,  Adam J. Mead,  Christina Halsey,  Irene Roberts,  Thomas A. Milne,  Anindita Roy.

Nature Communications
Volume: 12, Issue: 1, Pages: 6905.

miR-130b and miR-128a are essential lineage-specific codrivers of t(4;11) MLL-AF4 acute leukemia

Camille Malouf,  Eric T. B. Antunes,  Michael O’Dwyer,  Hélène Jakobczyk,  Franziska Sahm,  Sophie-Luise Landua,  Richard A. Anderson,  Abdenour Soufi,  Christina Halsey,  Katrin Ottersbach.

Blood
Volume: 138, Issue: 21, Pages: 2066-2092.

Karyosequencing: Integrating Genome-Wide and Targeted Sequencing for Comprehensive Diagnosis of Lymphoproliferative Disorders

James Peter Stewart,  Louise Harewood,  Shambhavi Srivastava,  Jana Gazdova,  Manisha Maurya,  Sirintra Nakjang,  Elizabeth Hodges,  Laura Chiecchio,  Nicholas C. P. Cross,  Matthew W Jenner,  Mark Catherwood,  Sarra Ryan,  Anthony V. Moorman,  Nikos Darzentas,  David Gonzalez.

Blood
Volume: 138, Pages: 272.

Anti-CD21 Chimeric Antigen Receptor (CAR)-T Cells for T Cell Acute Lymphoblastic Leukaemia (T-ALL)

Nicola C Maciocia,  Amy Burley,  Francesco Nannini,  Patrycja Wawrzyniecka,  Margarida Neves,  Thaneswari Karpanasamy,  Mathieu Ferrari,  Teresa Marafioti,  Shimobi Onuoha,  Asim Khwaja,  Paul M Maciocia,  Martin Pule.

Blood
Volume: 138, Issue: Supplement 1, Pages: 902.

Defining low-risk high hyperdiploidy in patients with paediatric acute lymphoblastic leukaemia: a retrospective analysis of data from the UKALL97/99 and UKALL2003 clinical trials

Amir Enshaei,  Ajay Vora,  Christine J Harrison,  John Moppett,  Anthony V Moorman.

The Lancet Haematology
Volume: 8, Issue: 11, Pages: e828-e839.

Frequency and Prognostic Impact of ALK Amplifications and Mutations in the European Neuroblastoma Study Group (SIOPEN) High-Risk Neuroblastoma Trial (HR-NBL1)

Angela Bellini,  Ulrike Pötschger,  Virginie Bernard,  Eve Lapouble,  Sylvain Baulande,  Peter F. Ambros,  Nathalie Auger,  Klaus Beiske,  Marie Bernkopf,  David R. Betts,  Jaydutt Bhalshankar,  Nick Bown,  Katleen de Preter,  Nathalie Clément,  Valérie Combaret,  Jaime Font de Mora,  Sally L. George,  Irene Jiménez,  Marta Jeison,  Barbara Marques,  Tommy Martinsson,  Katia Mazzocco,  Martina Morini,  Annick Mühlethaler-Mottet,  Rosa Noguera,  Gaelle Pierron,  Maria Rossing,  Sabine Taschner-Mandl,  Nadine Van Roy,  Ales Vicha,  Louis Chesler,  Walentyna Balwierz,  Victoria Castel,  Martin Elliott,  Per Kogner,  Geneviève Laureys,  Roberto Luksch,  Josef Malis,  Maja Popovic-Beck,  Shifra Ash,  Olivier Delattre,  Dominique Valteau-Couanet,  Deborah A. Tweddle,  Ruth Ladenstein,  Gudrun Schleiermacher.

Journal of Clinical Oncology
Volume: 39, Issue: 30, Pages: 3377-3390.

Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis

Chun Gong,  Joanna A. Krupka,  Jie Gao,  Nicholas F. Grigoropoulos,  George Giotopoulos,  Ryan Asby,  Michael Screen,  Zelvera Usheva,  Francesco Cucco,  Sharon Barrans,  Daniel Painter,  Nurmahirah Binte Mohammed Zaini,  Björn Haupl,  Susanne Bornelöv,  Igor Ruiz De Los Mozos,  Wei Meng,  Peixun Zhou,  Alex E. Blain,  Sorcha Forde,  Jamie Matthews,  Michelle Guet Khim Tan,  G. A. Amos Burke,  Siu Kwan Sze,  Philip Beer,  Cathy Burton,  Peter Campbell,  Vikki Rand,  Suzanne D. Turner,  Jernej Ule,  Eve Roman,  Reuben Tooze,  Thomas Oellerich,  Brian J. Huntly,  Martin Turner,  Ming-Qing Du,  Shamith A. Samarajiwa,  Daniel J. Hodson.

Molecular Cell
Volume: 81, Issue: 19, Pages: 4059-4075.e11.

Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis

Chun Gong,  Joanna A. Krupka,  Jie Gao,  Nicholas F. Grigoropoulos,  George Giotopoulos,  Ryan Asby,  Michael Screen,  Zelvera Usheva,  Francesco Cucco,  Sharon Barrans,  Daniel Painter,  Nurmahirah Binte Mohammed Zaini,  Björn Haupl,  Susanne Bornelöv,  Igor Ruiz De Los Mozos,  Wei Meng,  Peixun Zhou,  Alex E. Blain,  Sorcha Forde,  Jamie Matthews,  Michelle Guet Khim Tan,  G. A. Amos Burke,  Siu Kwan Sze,  Philip Beer,  Cathy Burton,  Peter Campbell,  Vikki Rand,  Suzanne D. Turner,  Jernej Ule,  Eve Roman,  Reuben Tooze,  Thomas Oellerich,  Brian J. Huntly,  Martin Turner,  Ming-Qing Du,  Shamith A. Samarajiwa,  Daniel J. Hodson.

Molecular Cell
Volume: 81, Issue: 19, Pages: 4059-4075.e11.

Minimal residual disease, long-term outcome, and IKZF1 deletions in children and adolescents with Down syndrome and acute lymphocytic leukaemia: a matched cohort study

Naomi Michels,  Judith M Boer,  Amir Enshaei,  Rosemary Sutton,  Mats Heyman,  Sabine Ebert,  Marta Fiocco,  Hester A de Groot-Kruseman,  Vincent H J van der Velden,  Gisela Barbany,  Gabriele Escherich,  Ajay Vora,  Toby Trahair,  Luciano Dalla-Pozza,  Rob Pieters,  Udo zur Stadt,  Kjeld Schmiegelow,  Anthony V Moorman,  C Michel Zwaan,  Monique L den Boer.

The Lancet Haematology
Volume: 8, Issue: 10, Pages: e700-e710.

Genome-wide analyses of XRN1-sensitive targets in osteosarcoma cells identify disease-relevant transcripts containing G-rich motifs

Amy L. Pashler,  Benjamin P. Towler,  Christopher I. Jones,  Hope J. Haime,  Tom Burgess,  Sarah F. Newbury.

RNA
Volume: 27, Issue: 10, Pages: 1265-1280.

Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study

Judith M. Boer,  Maria Grazia Valsecchi,  Femke M. Hormann,  Željko Antic,  Marketa Zaliova,  Claire Schwab,  Giovanni Cazzaniga,  Chloé Arfeuille,  Hélène Cavé,  Andishe Attarbaschi,  Sabine Strehl,  Gabriele Escherich,  Toshihiko Imamura,  Kentaro Ohki,  Tanja A. Grüber,  Rosemary Sutton,  Agata Pastorczak,  Tim Lammens,  Frédéric Lambert,  Chi Kong Li,  Enrique Carrillo de Santa Pau,  Steve Hoffmann,  Anja Möricke,  Christine J. Harrison,  Monique L. Den Boer,  Paola De Lorenzo,  Ronald W. Stam,  Anke K. Bergmann,  Rob Pieters.

Leukemia
Volume: 35, Issue: 10, Pages: 2978-2982.

DNA-TG and risk of sinusoidal obstruction syndrome in childhood acute lymphoblastic leukemia

Linea Natalie Toksvang,  Kathrine Grell,  Stine Nygaard Nielsen,  Jacob Nersting,  Daniel Murdy,  Anthony V. Moorman,  Ajay Vora,  Kjeld Schmiegelow.

Leukemia
Volume: 36, Pages: 555-557.

Non-toxic polymer nanovectors for improved delivery of dexamethasone

Benjamin C. Ede,  Paraskevi Diamanti,  David S. Williams,  Allison Blair.

Scientific Reports
Volume: 11, Issue: 1, Pages: 17263.

Comparison of Osteosarcoma Aggregated Tumour Models with Human Tissue by Multimodal Mass Spectrometry Imaging

Lucy E. Flint,  Gregory Hamm,  Joseph D. Ready,  Stephanie Ling,  Catherine J. Duckett,  Neil A. Cross,  Laura M. Cole,  David P. Smith,  Richard J. A. Goodwin,  Malcolm R. Clench.

Metabolites
Volume: 11, Issue: 8, Pages: 506.

Comparison of Osteosarcoma Aggregated Tumour Models with Human Tissue by Multimodal Mass Spectrometry Imaging

Lucy E. Flint,  Gregory Hamm,  Joseph D. Ready,  Stephanie Ling,  Catherine J. Duckett,  Neil A. Cross,  Laura M. Cole,  David P. Smith,  Richard J. A. Goodwin,  Malcolm R. Clench.

Metabolites
Volume: 11, Issue: 8, Pages: 506.

Genome-wide analyses of XRN1-sensitive targets in osteosarcoma cells identifies disease-relevant transcripts containing G-rich motifs.

Amy L. Pashler,  Benjamin P. Towler,  Christopher I. Jones,  Hope J. Haime,  Tom Burgess,  Sarah F. Newbury.

RNA
Pages: rna.078872.121.

Abstract 2120: Interrogation of regulatory and expression changes in Malignant Rhabdoid Tumours to identify new therapeutic approaches

Emma L. Lishman-Walker,  Martina A. Finetti,  James P. Hacking,  Matthew Selby,  Yura Grabovska,  Stephen Crosier,  Simon Bailey,  Steven C. Clifford,  Daniel Williamson.

Cancer Research
Volume: 81, Issue: 13_Supplement, Pages: 2120.

Risk factors and outcomes in children with high-risk B-cell precursor and T-cell relapsed acute lymphoblastic leukaemia: combined analysis of ALLR3 and ALL-REZ BFM 2002 clinical trials

Cornelia Eckert,  Catriona Parker,  Anthony V. Moorman,  Julie Ae Irving,  Renate Kirschner-Schwabe,  Stefanie Groeneveld-Krentz,  Tamas Révész,  Peter Hoogerbrugge,  Jeremy Hancock,  Rosemary Sutton,  Guenter Henze,  Christiane Chen-Santel,  Andishe Attarbaschi,  Jean-Pierre Bourquin,  Lucie Sramkova,  Martin Zimmermann,  Shekhar Krishnan,  Arend von Stackelberg,  Vaskar Saha.

European Journal of Cancer (Oxford, England: 1990)
Volume: 151, Pages: 175-189.

MYB rearrangements and over-expression in T-cell acute lymphoblastic leukemia

Valentina Bardelli,  Silvia Arniani,  Valentina Pierini,  Tiziana Pierini,  Danika Di Giacomo,  Paolo Gorello,  Martina Moretti,  Fabrizia Pellanera,  Loredana Elia,  Antonella Vitale,  Clelia Tiziana Storlazzi,  Doron Tolomeo,  Elena Mastrodicasa,  Maurizio Caniglia,  Sabina Chiaretti,  Loredana Ruggeri,  Giovanni Roti,  Claire Schwab,  Christine J. Harrison,  André Almeida,  Tim Pieters,  Pieter Van Vlierberghe,  Cristina Mecucci,  Roberta La Starza.

Genes, Chromosomes & Cancer
Volume: 60, Issue: 7, Pages: 482-488.

Dissecting the Transcriptional and Chromatin Accessibility Heterogeneity of Proliferating Cone Precursors in Human Retinoblastoma Tumors by Single Cell Sequencing—Opening Pathways to New Therapeutic Strategies?

Joseph Collin,  Rachel Queen,  Darin Zerti,  David H Steel,  Claire Bowen,  Manoj Parulekar,  Majlinda Lako.

Investigative Ophthalmology & Visual Science
Volume: 62, Issue: 6, Pages: 18.

STAT3 and TP53 mutations associate with poor prognosis in anaplastic large cell lymphoma

Cosimo Lobello,  Boris Tichy,  Vojtech Bystry,  Lenka Radova,  Daniel Filip,  Marek Mraz,  Ivonne-Aidee Montes-Mojarro,  Nina Prokoph,  Hugo Larose,  Huan-Chang Liang,  Geeta G. Sharma,  Luca Mologni,  David Belada,  Katerina Kamaradova,  Falko Fend,  Carlo Gambacorti-Passerini,  Olaf Merkel,  Suzanne D. Turner,  Andrea Janikova,  Sarka Pospisilova.

Leukemia
Volume: 35, Issue: 5, Pages: 1500-1505.

Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation

Sara Badodi,  Nicola Pomella,  Xinyu Zhang,  Gabriel Rosser,  John Whittingham,  Maria Victoria Niklison-Chirou,  Yau Mun Lim,  Sebastian Brandner,  Gillian Morrison,  Steven M. Pollard,  Christopher D. Bennett,  Steven C. Clifford,  Andrew Peet,  M. Albert Basson,  Silvia Marino.

Nature Communications
Volume: 12, Issue: 1, Pages: 2148.

SSBP2-CSF1R is a recurrent fusion in B-lineage acute lymphoblastic leukemia with diverse genetic presentation and variable outcome

Claire Schwab,  Kathryn Roberts,  Judith M. Boer,  Gudrun Göhring,  Doris Steinemann,  Ajay Vora,  Christine Macartney,  Rachael Hough,  Zoe Thorn,  Richard Dillon,  Gabriele Escherich,  Giovanni Cazzaniga,  Brigitte Schlegelberger,  Mignon Loh,  Monique L. den Boer,  Anthony V. Moorman,  Christine J. Harrison.

Blood
Volume: 137, Issue: 13, Pages: 1835-1838.

Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours

Lars Custers,  Eleonora Khabirova,  Tim H. H. Coorens,  Thomas R. W. Oliver,  Camilla Calandrini,  Matthew D. Young,  Felipe A. Vieira Braga,  Peter Ellis,  Lira Mamanova,  Heidi Segers,  Arie Maat,  Marcel Kool,  Eelco W. Hoving,  Marry M. van den Heuvel-Eibrink,  James Nicholson,  Karin Straathof,  Liz Hook,  Ronald R. de Krijger,  Claire Trayers,  Kieren Allinson,  Sam Behjati,  Jarno Drost.

Nature Communications
Volume: 12, Issue: 1, Pages: 1407.

The <i>EBF1-PDGFRB</i> T681I mutation is highly resistant to imatinib and dasatinib <i>in vitro</i> and detectable in clinical samples prior to treatment

Thai Hoa Tran,  Jonathan V. Nguyen,  Adrian Stecula,  Jon Akutagawa,  Anthony V. Moorman,  Benjamin S. Braun,  Andrej Sali,  Charles G. Mullighan,  Neil P. Shah,  Yunfeng Dai,  Meenakshi Devidas,  Kathryn G. Roberts,  Catherine C. Smith,  Mignon L. Loh.

Haematologica
Volume: 106, Issue: 8, Pages: 2242-2245.

The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis

Ivo S. Muskens,  Shaobo Li,  Thomas Jackson,  Natalina Elliot,  Helen M. Hansen,  Swe Swe Myint,  Priyatama Pandey,  Jeremy M. Schraw,  Ritu Roy,  Joaquin Anguiano,  Katerina Goudevenou,  Kimberly D. Siegmund,  Philip J. Lupo,  Marella F. T. R. de Bruijn,  Kyle M. Walsh,  Paresh Vyas,  Xiaomei Ma,  Anindita Roy,  Irene Roberts,  Joseph L. Wiemels,  Adam J. de Smith.

Nature Communications
Volume: 12, Issue: 1, Pages: 821.

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia

Eleni Louka,  Benjamin Povinelli,  Alba Rodriguez-Meira,  Gemma Buck,  Wei Xiong Wen,  Guanlin Wang,  Nikolaos Sousos,  Neil Ashley,  Angela Hamblin,  Christopher A.G. Booth,  Anindita Roy,  Natalina Elliott,  Deena Iskander,  Josu de la Fuente,  Nicholas Fordham,  Sorcha O’Byrne,  Sarah Inglott,  Ruggiero Norfo,  Mariolina Salio,  Supat Thongjuea,  Anupama Rao,  Irene Roberts,  Adam J. Mead.

Journal of Experimental Medicine
Volume: 218, Issue: 2.

Integrative molecular characterization of pediatric spinal ependymoma: the UK Children’s Cancer and Leukaemia Group study

Omar Ahmad,  Rebecca Chapman,  Lisa C Storer,  Li Luo,  Paul R Heath,  Linda Resar,  Kenneth J Cohen,  Richard G Grundy,  Anbarasu Lourdusamy.

Neuro-Oncology Advances
Volume: 3, Issue: 1, Pages: vdab043.

H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells

Laura Godfrey,  Nicholas T. Crump,  Sorcha O’Byrne,  I.-Jun Lau,  Siobhan Rice,  Joe R. Harman,  Thomas Jackson,  Natalina Elliott,  Gemma Buck,  Christopher Connor,  Ross Thorne,  David J. H. F. Knapp,  Olaf Heidenreich,  Paresh Vyas,  Pablo Menendez,  Sarah Inglott,  Philip Ancliff,  Huimin Geng,  Irene Roberts,  Anindita Roy,  Thomas A. Milne.

Leukemia
Volume: 35, Issue: 1, Pages: 90-106.

H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells

Laura Godfrey,  Nicholas T. Crump,  Sorcha O’Byrne,  I.-Jun Lau,  Siobhan Rice,  Joe R. Harman,  Thomas Jackson,  Natalina Elliott,  Gemma Buck,  Christopher Connor,  Ross Thorne,  David J. H. F. Knapp,  Olaf Heidenreich,  Paresh Vyas,  Pablo Menendez,  Sarah Inglott,  Philip Ancliff,  Huimin Geng,  Irene Roberts,  Anindita Roy,  Thomas A. Milne.

Leukemia
Volume: 35, Issue: 1, Pages: 90-106.

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay

Gaëtan Juban,  Nathalie Sakakini,  Hedia Chagraoui,  David Cruz Hernandez,  Qian Cheng,  Kelly Soady,  Bilyana Stoilova,  Catherine Garnett,  Dominic Waithe,  Georg Otto,  Jessica Doondeea,  Batchimeg Usukhbayar,  Elena Karkoulia,  Maria Alexiou,  John Strouboulis,  Edward Morrissey,  Irene Roberts,  Catherine Porcher,  Paresh Vyas.

Haematologica
Volume: 106, Issue: 4, Pages: 1106-1119.

Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics

Stephen Crosier,  Debbie Hicks,  Edward C. Schwalbe,  Daniel Williamson,  Sarah Leigh Nicholson,  Amanda Smith,  Janet C. Lindsey,  Antony Michalski,  Barry Pizer,  Simon Bailey,  Nick Bown,  Gavin Cuthbert,  Stephen B. Wharton,  Thomas S. Jacques,  Abhijit Joshi,  Steven C. Clifford.

Neuropathology and Applied Neurobiology
Volume: 47, Issue: 6, Pages: 736-747.

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay

Gaëtan Juban,  Nathalie Sakakini,  Hedia Chagraoui,  David Cruz Hernandez,  Qian Cheng,  Kelly Soady,  Bilyana Stoilova,  Catherine Garnett,  Dominic Waithe,  Georg Otto,  Jessica Doondeea,  Batchimeg Usukhbayar,  Elena Karkoulia,  Maria Alexiou,  John Strouboulis,  Edward Morrissey,  Irene Roberts,  Catherine Porcher,  Paresh Vyas.

Haematologica
Volume: 106, Issue: 4, Pages: 1106-1119.

Clinical characteristics and outcomes of children with WAGR syndrome and Wilms tumor and/or nephroblastomatosis: The 30-year SIOP-RTSG experience

Janna A. Hol,  Marjolijn C. J. Jongmans,  Hélène Sudour-Bonnange,  Gema L. Ramírez-Villar,  Tanzina Chowdhury,  Catherine Rechnitzer,  Niklas Pal,  Gudrun Schleiermacher,  Axel Karow,  Roland P. Kuiper,  Beatriz de Camargo,  Simona Avcin,  Danka Redzic,  Antonio Wachtel,  Heidi Segers,  Gordan M. Vujanic,  Harm van Tinteren,  Christophe Bergeron,  Kathy Pritchard-Jones,  Norbert Graf,  Marry M. van den Heuvel-Eibrink,  for the International Society of Pediatric Oncology Renal Tumor Study Group (SIOP-RTSG).

Cancer
Volume: 127, Issue: 4, Pages: 628-638.

Single nucleotide polymorphism array-based signature of low hypodiploidy in acute lymphoblastic leukemia

Thomas Creasey,  Amir Enshaei,  Karin Nebral,  Claire Schwab,  Kathryn Watts,  Gavin Cuthbert,  Ajay Vora,  John Moppett,  Christine J. Harrison,  Adele K. Fielding,  Oskar A. Haas,  Anthony V. Moorman.

Genes, Chromosomes and Cancer
Volume: 60, Issue: 9, Pages: 604-615.

Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target

Hugo Larose,  Nina Prokoph,  Jamie D. Matthews,  Michaela Schlederer,  Sandra Högler,  Ali F. Alsulami,  Stephen P. Ducray,  Edem Nuglozeh,  Feroze M. S. Fazaludeen,  Ahmed Elmouna,  Monica Ceccon,  Luca Mologni,  Carlo Gambacorti-Passerini,  Gerald Hoefler,  Cosimo Lobello,  Sarka Pospisilova,  Andrea Janikova,  Wilhelm Woessmann,  Christine Damm-Welk,  Martin Zimmermann,  Alina Federova,  Andrea Malone,  Owen Smith,  Mariusz Wasik,  Giorgio Inghirami,  Laurence Lamant,  Tom L. Blundell,  Wolfram Klapper,  Olaf Merkel,  G. A. Amos Burke,  Shahid Mian,  Ibraheem Ashankyty,  Lukas Kenner,  Suzanne D. Turner.

Haematologica
Volume: 106, Issue: 6, Pages: 1693-1704.

Characteristics and outcome of pediatric renal cell carcinoma patients registered in the International Society of Pediatric Oncology (SIOP) 93-01, 2001 and UK-IMPORT database: A report of the SIOP-Renal Tumor Study Group

Justine N. van der Beek,  Janna A. Hol,  Aurore Coulomb-l'Hermine,  Norbert Graf,  Harm van Tinteren,  Kathy Pritchard-Jones,  Maite E. Houwing,  Ronald R. de Krijger,  Gordan M. Vujanic,  Kristina Dzhuma,  Jens-Peter Schenk,  Annemieke S. Littooij,  Gema L. Ramírez-Villar,  Dermot Murphy,  Satyajit Ray,  Reem Al-Saadi,  Manfred Gessler,  Jan Godzinski,  Christian Ruebe,  Paola Collini,  Arnaud C. Verschuur,  Tony Frisk,  Christian Vokuhl,  Christina A. Hulsbergen-van de Kaa,  Beatriz de Camargo,  Bengt Sandstedt,  Barbara Selle,  Godelieve A. M. Tytgat,  Marry M. van den Heuvel-Eibrink.

International Journal of Cancer
Volume: 148, Issue: 11, Pages: 2724-2735.

The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second-generation subtypes

D. Hicks,  G. Rafiee,  E. C. Schwalbe,  C. I. Howell,  J. C. Lindsey,  R. M. Hill,  A. J. Smith,  P. Adidharma,  C. Steel,  S. Richardson,  L. Pease,  M. Danilenko,  S. Crosier,  A. Joshi,  S. B. Wharton,  T. S. Jacques,  B. Pizer,  A. Michalski,  D. Williamson,  S. Bailey,  S. C. Clifford.

Neuropathology and Applied Neurobiology
Volume: 47, Issue: 2, Pages: 236-250.

Dis3L2 regulates cell proliferation and tissue growth through a conserved mechanism

Benjamin P. Towler,  Amy L. Pashler,  Hope J. Haime,  Katarzyna M. Przybyl,  Sandra C. Viegas,  Rute G. Matos,  Simon J. Morley,  Cecilia M. Arraiano,  Sarah F. Newbury.

PLOS Genetics
Volume: 16, Issue: 12, Pages: e1009297.

Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study

Rebecca M Hill,  Stacey Richardson,  Edward C Schwalbe,  Debbie Hicks,  Janet C Lindsey,  Stephen Crosier,  Gholamreza Rafiee,  Yura Grabovska,  Stephen B Wharton,  Thomas S Jacques,  Antony Michalski,  Abhijit Joshi,  Barry Pizer,  Daniel Williamson,  Simon Bailey,  Steven C Clifford.

The Lancet Child & Adolescent Health
Volume: 4, Issue: 12, Pages: 865-874.

Biodegradable Nanovectors As a Direct Platform for the Controlled Delivery of Chemotherapeutic Drugs Against Childhood ALL

Benjamin C Ede,  Paraskevi Diamanti,  David C Williams,  Allison Blair.

Blood
Volume: 136, Issue: Supplement 1, Pages: 9.

Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable MYCN-Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group

Inge M. Ambros,  Gian-Paolo Tonini,  Ulrike Pötschger,  Nicole Gross,  Véronique Mosseri,  Klaus Beiske,  Ana P. Berbegall,  Jean Bénard,  Nick Bown,  Huib Caron,  Valérie Combaret,  Jerome Couturier,  Raffaella Defferrari,  Olivier Delattre,  Marta Jeison,  Per Kogner,  John Lunec,  Barbara Marques,  Tommy Martinsson,  Katia Mazzocco,  Rosa Noguera,  Gudrun Schleiermacher,  Alexander Valent,  Nadine Van Roy,  Eva Villamon,  Dasa Janousek,  Ingrid Pribill,  Evgenia Glogova,  Edward F. Attiyeh,  Michael D. Hogarty,  Tom F. Monclair,  Keith Holmes,  Dominique Valteau-Couanet,  Victoria Castel,  Deborah A. Tweddle,  Julie R. Park,  Sue Cohn,  Ruth Ladenstein,  Maja Beck-Popovic,  Bruno De Bernardi,  Jean Michon,  Andrew D. J. Pearson,  Peter F. Ambros.

Journal of Clinical Oncology
Volume: 38, Issue: 31, Pages: 3685-3697.

VEGFC negatively regulates the growth and aggressiveness of medulloblastoma cells

Manon Penco-Campillo,  Yannick Comoglio,  Álvaro Javier Feliz Morel,  Rita Hanna,  Jérôme Durivault,  Magalie Leloire,  Bastien Mejias,  Marina Pagnuzzi,  Amandine Morot,  Fanny Burel-Vandenbos,  Matthew Selby,  Daniel Williamson,  Steven C. Clifford,  Audrey Claren,  Jérôme Doyen,  Vincent Picco,  Sonia Martial,  Gilles Pagès.

Communications Biology
Volume: 3, Issue: 1, Pages: 1-14.

CD1a is rarely expressed in pediatric or adult relapsed/refractory T-ALL: implications for immunotherapy

Sarah Leong,  Sarah Inglott,  Foteini Papaleonidopoulou,  Karen Orfinada,  Philip Ancliff,  Jack Bartram,  Ben Carpenter,  Adele K. Fielding,  Sara Ghorashian,  Victoria Grandage,  Rajeev Gupta,  Rachael Hough,  Asim Khwaja,  Vesna Pavasovic,  Anupama Rao,  Sujith Samarasinghe,  Ajay Vora,  Marc R. Mansour,  David O’Connor.

Blood Advances
Volume: 4, Issue: 19, Pages: 4665-4668.

Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment depends on stearoyl-CoA desaturase

Angela Maria Savino,  Sara Isabel Fernandes,  Orianne Olivares,  Anna Zemlyansky,  Antony Cousins,  Elke K. Markert,  Shani Barel,  Ifat Geron,  Liron Frishman,  Yehudit Birger,  Cornelia Eckert,  Sergey Tumanov,  Gillian MacKay,  Jurre J. Kamphorst,  Pawel Herzyk,  Jonatan Fernández-García,  Ifat Abramovich,  Inbal Mor,  Michela Bardini,  Ersilia Barin,  Sudha Janaki-Raman,  Justin R. Cross,  Michael G. Kharas,  Eyal Gottlieb,  Shai Izraeli,  Christina Halsey.

Nature Cancer
Volume: 1, Issue: 10, Pages: 998-1009.

Sensitive, rapid diagnostic test for transient abnormal myelopoiesis and myeloid leukemia of Down syndrome

David Cruz Hernandez,  Marlen Metzner,  Anne Pieta de Groot,  Batchimeg Usukhbayar,  Natalina Elliott,  Irene Roberts,  Paresh Vyas.

Blood
Volume: 136, Issue: 12, Pages: 1460-1465.

Characterization of an Aggregated Three-Dimensional Cell Culture Model by Multimodal Mass Spectrometry Imaging

Lucy E. Flint,  Gregory Hamm,  Joseph D. Ready,  Stephanie Ling,  Catherine J. Duckett,  Neil A. Cross,  Laura M. Cole,  David P. Smith,  Richard J. A. Goodwin,  Malcolm R. Clench.

Analytical Chemistry
Volume: 92, Issue: 18, Pages: 12538-12547.

Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity

Yura Grabovska,  Alan Mackay,  Patricia O’Hare,  Stephen Crosier,  Martina Finetti,  Edward C. Schwalbe,  Jessica C. Pickles,  Amy R. Fairchild,  Aimee Avery,  Julia Cockle,  Rebecca Hill,  Janet Lindsey,  Debbie Hicks,  Mark Kristiansen,  Jane Chalker,  John Anderson,  Darren Hargrave,  Thomas S. Jacques,  Karin Straathof,  Simon Bailey,  Chris Jones,  Steven C. Clifford,  Daniel Williamson.

Nature Communications
Volume: 11, Issue: 1, Pages: 4324.

Leveraging Genome and Phenome-Wide Association Studies to Investigate Genetic Risk of Acute Lymphoblastic Leukemia

Eleanor C. Semmes,  Jayaram Vijayakrishnan,  Chenan Zhang,  Jillian H. Hurst,  Richard S. Houlston,  Kyle M. Walsh.

Cancer Epidemiology and Prevention Biomarkers
Volume: 29, Issue: 8, Pages: 1606-1614.

Phenotypic analysis of an MLL-AF4 gene regulatory network reveals indirect CASP9 repression as a mode of inducing apoptosis resistance

Joe R. Harman,  Ross Thorne,  Max Jamilly,  Marta Tapia,  Nicholas T. Crump,  Siobhan Rice,  Ryan Beveridge,  Edward Morrissey,  Marella F. T. R. de Bruijn,  Irene Roberts,  Anindita Roy,  Tudor A. Fulga,  Thomas A. Milne.

bioRxiv
Pages: 2020.06.30.179796.

Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review

Justine N. van der Beek,  James I. Geller,  Ronald R. de Krijger,  Norbert Graf,  Kathy Pritchard-Jones,  Jarno Drost,  Arnauld C. Verschuur,  Dermot Murphy,  Satyajit Ray,  Filippo Spreafico,  Kristina Dzhuma,  Annemieke S. Littooij,  Barbara Selle,  Godelieve A. M. Tytgat,  Marry M. van den Heuvel-Eibrink.

Cancers
Volume: 12, Issue: 7, Pages: 1776.

Molecular subgrouping of atypical teratoid/rhabdoid tumors—a reinvestigation and current consensus

Ben Ho,  Pascal D Johann,  Yura Grabovska,  Mamy Jean De Dieu Andrianteranagna,  Fupan Yao,  Michael Frühwald,  Martin Hasselblatt,  Franck Bourdeaut,  Daniel Williamson,  Annie Huang,  Marcel Kool.

Neuro-Oncology
Volume: 22, Issue: 5, Pages: 613-624.

Design of a Comprehensive Fluorescence in Situ Hybridization Assay for Genetic Classification of T-Cell Acute Lymphoblastic Leukemia

Roberta La Starza,  Valentina Pierini,  Tiziana Pierini,  Valeria Nofrini,  Caterina Matteucci,  Silvia Arniani,  Martina Moretti,  Anair G. Lema Fernandez,  Fabrizia Pellanera,  Danika Di Giacomo,  Tiziana C. Storlazzi,  Antonella Vitale,  Paolo Gorello,  Gabriella Sammarelli,  Giovanni Roti,  Giuseppe Basso,  Sabina Chiaretti,  Robin Foà,  Claire Schwab,  Christine J. Harrison,  Pieter Van Vlierberghe,  Cristina Mecucci.

The Journal of Molecular Diagnostics
Volume: 22, Issue: 5, Pages: 629-639.

Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target

Hugo Larose,  Nina Prokoph,  Jamie D. Matthews,  Michaela Schlederer,  Sandra Högler,  Ali F. Alsulami,  Stephen P. Ducray,  Edem Nuglozeh,  Feroze M.S. Fazaludeen,  Ahmed Elmouna,  Monica Ceccon,  Luca Mologni,  Carlo Gambacorti-Passerini,  Gerald Hoefler,  Cosimo Lobello,  Sarka Pospisilova,  Andrea Janikova,  Wilhelm Woessmann,  Christine Damm-Welk,  Martin Zimmermann,  Alina Federova,  Andrea Malone,  Owen Smith,  Mariusz Wasik,  Giorgio Inghirami,  Laurence Lamant,  Tom L. Blundell,  Wolfram Klapper,  Olaf Merkel,  G.A. Amos Burke,  Shahid Mian,  Ibraheem Ashankyty,  Lukas Kenner,  Suzanne D. Turner.

Haematologica
Volume: 106, Issue: 6, Pages: 1693-1704.

A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia

Amir Enshaei,  David O’Connor,  Jack Bartram,  Jeremy Hancock,  Christine J. Harrison,  Rachael Hough,  Sujith Samarasinghe,  Monique L. den Boer,  Judith M. Boer,  Hester A. de Groot-Kruseman,  Hanne V. Marquart,  Ulrika Noren-Nystrom,  Kjeld Schmiegelow,  Claire Schwab,  Martin A. Horstmann,  Gabriele Escherich,  Mats Heyman,  Rob Pieters,  Ajay Vora,  John Moppett,  Anthony V. Moorman.

Blood
Volume: 135, Issue: 17, Pages: 1438-1446.

H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells

Laura Godfrey,  Nicholas T. Crump,  Sorcha O’Byrne,  I-Jun Lau,  Siobhan Rice,  Joe R. Harman,  Thomas Jackson,  Natalina Elliott,  Gemma Buck,  Christopher Connor,  Ross Thorne,  David J. H. F. Knapp,  Olaf Heidenreich,  Paresh Vyas,  Pablo Menendez,  Sarah Inglott,  Philip Ancliff,  Huimin Geng,  Irene Roberts,  Anindita Roy,  Thomas A. Milne.

Leukemia

Translational genomics of malignant rhabdoid tumours: Current impact and future possibilities

Martina A. Finetti,  Yura Grabovska,  Simon Bailey,  Daniel Williamson.

Seminars in Cancer Biology
Volume: 61, Pages: 30-41.

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity

Camilla Calandrini,  Frans Schutgens,  Rurika Oka,  Thanasis Margaritis,  Tito Candelli,  Luka Mathijsen,  Carola Ammerlaan,  Ravian L. van Ineveld,  Sepide Derakhshan,  Sanne de Haan,  Emmy Dolman,  Philip Lijnzaad,  Lars Custers,  Harry Begthel,  Hindrik H. D. Kerstens,  Lindy L. Visser,  Maarten Rookmaaker,  Marianne Verhaar,  Godelieve A. M. Tytgat,  Patrick Kemmeren,  Ronald R. de Krijger,  Reem Al-Saadi,  Kathy Pritchard-Jones,  Marcel Kool,  Anne C. Rios,  Marry M. van den Heuvel-Eibrink,  Jan J. Molenaar,  Ruben van Boxtel,  Frank C. P. Holstege,  Hans Clevers,  Jarno Drost.

Nature Communications
Volume: 11, Issue: 1, Pages: 1310.

Outcome of patients with stage IV high-risk Wilms tumour treated according to the SIOP2001 protocol: A report of the SIOP Renal Tumour Study Group

Claudia Pasqualini,  Rhoikos Furtwängler,  Harm van Tinteren,  Roberto A. P. Teixeira,  Tomas Acha,  Lisa Howell,  Gordan Vujanic,  Jan Godzinski,  Patrick Melchior,  Anne M. Smets,  Aurore Coulomb-L’Hermine,  Hervé Brisse,  Kathy Pritchard-Jones,  Christophe Bergeron,  Beatriz de Camargo,  Marry M. van den Heuvel-Eibrink,  Norbert Graf,  Arnauld C. Verschuur.

European Journal of Cancer
Volume: 128, Pages: 38-46.

The role of imaging in the initial investigation of paediatric renal tumours

Tom Watson,  Minou Oostveen,  Harriet Rogers,  Kathy Pritchard-Jones,  Øystein Olsen.

The Lancet Child & Adolescent Health
Volume: 4, Issue: 3, Pages: 232-241.

Germline variants in predisposition genes in children with Down syndrome and acute lymphoblastic leukemia

Peleg Winer,  Ivo S. Muskens,  Kyle M. Walsh,  Ajay Vora,  Anthony V. Moorman,  Joseph L. Wiemels,  Irene Roberts,  Anindita Roy,  Adam J. de Smith.

Blood Advances
Volume: 4, Issue: 4, Pages: 672-675.

Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study

Bryan K. Li,  Alexandre Vasiljevic,  Christelle Dufour,  Fupan Yao,  Ben L. B. Ho,  Mei Lu,  Eugene I. Hwang,  Sridharan Gururangan,  Jordan R. Hansford,  Maryam Fouladi,  Sumihito Nobusawa,  Annie Laquerriere,  Marie-Bernadette Delisle,  Jason Fangusaro,  Fabien Forest,  Helen Toledano,  Palma Solano-Paez,  Sarah Leary,  Diane Birks,  Lindsey M. Hoffman,  Alexandru Szathmari,  Cécile Faure-Conter,  Xing Fan,  Daniel Catchpoole,  Li Zhou,  Kris Ann P. Schultz,  Koichi Ichimura,  Guillaume Gauchotte,  Nada Jabado,  Chris Jones,  Delphine Loussouarn,  Karima Mokhtari,  Audrey Rousseau,  David S. Ziegler,  Shinya Tanaka,  Scott L. Pomeroy,  Amar Gajjar,  Vijay Ramaswamy,  Cynthia Hawkins,  Richard G. Grundy,  D. Ashley Hill,  Eric Bouffet,  Annie Huang,  Anne Jouvet.

Acta Neuropathologica
Volume: 139, Issue: 2, Pages: 223-241.

DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study

Jessica C Pickles,  Amy R Fairchild,  Thomas J Stone,  Lorelle Brownlee,  Ashirwad Merve,  Shireena A Yasin,  Aimee Avery,  Saira W Ahmed,  Olumide Ogunbiyi,  Jamie Gonzalez Zapata,  Abigail F Peary,  Marie Edwards,  Lisa Wilkhu,  Carryl Dryden,  Dariusz Ladon,  Mark Kristiansen,  Catherine Rowe,  Kathreena M Kurian,  James A R Nicoll,  Clare Mitchell,  Tabitha Bloom,  David A Hilton,  Safa Al-Sarraj,  Lawrence Doey,  Paul N Johns,  Leslie R Bridges,  Aruna Chakrabarty,  Azzam Ismail,  Nitika Rathi,  Khaja Syed,  G Alistair Lammie,  Clara Limback-Stanic,  Colin Smith,  Antonia Torgersen,  Frances Rae,  Rebecca M Hill,  Steven C Clifford,  Yura Grabovska,  Daniel Williamson,  Matthew Clarke,  Chris Jones,  David Capper,  Martin Sill,  Andreas von Deimling,  Stefan M Pfister,  David T W Jones,  Darren Hargrave,  Jane Chalker,  Thomas S Jacques.

The Lancet Child & Adolescent Health
Volume: 4, Issue: 2, Pages: 121-130.

The AHR pathway represses TGFß-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma

Nemanja Saric,  Matthew Selby,  Vijay Ramaswamy,  Marcel Kool,  Brigitta Stockinger,  Christer Hogstrand,  Daniel Williamson,  Silvia Marino,  Michael D. Taylor,  Steven C. Clifford,  M. Albert Basson.

Scientific Reports
Volume: 10, Issue: 1, Pages: 148.

Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia

Matthew Bashton,  Robin Hollis,  Sarra Ryan,  Claire J. Schwab,  John Moppett,  Christine J. Harrison,  Anthony V. Moorman,  Amir Enshaei.

Scientific Reports
Volume: 10, Issue: 1, Pages: 45.

Is radiotherapy required in first-line treatment of stage I diffuse anaplastic Wilms tumor? A report of SIOP-RTSG, AIEOP, JWiTS, and UKCCSG

Raquel Dávila Fajardo,  Marry M. van den Heuvel-Eibrink,  Harm van Tinteren,  Filippo Spreafico,  Thomas Acha,  Christophe Bergeron,  Beatriz de Camargo,  Foppe Oldenburger,  Christian Rübe,  Takaharu Oue,  Christian Vokuhl,  Ronald R. de Krijger,  Gordan Vujanic,  Neil Sebire,  Aurore Coulomb-L'Hermine,  Paola Collini,  Lorenza Gandola,  Kathy Pritchard-Jones,  Norbert Graf,  Geert O. Janssens,  Martine van Grotel.

Pediatric Blood & Cancer
Volume: 67, Issue: 2, Pages: e28039.

Pediatric and young adult renal cell carcinoma

Satyajit Ray,  Robert Jones,  Kathy Pritchard-Jones,  Kristina Dzhuma,  Marry van den Heuvel-Eibrink,  Godelieve Tytgat,  Justine van der Beek,  Grenville Oades,  Dermot Murphy.

Pediatric Blood & Cancer
Volume: 67, Issue: 11, Pages: e28675.

Molecular characterisation and clinical outcome of B-cell precursor acute lymphoblastic leukaemia with IG-MYC rearrangement

Simon Bomken,  Amir Enshaei,  Edward C. Schwalbe,  Aneta Mikulasova,  Yunfeng Dai,  Masood Zaka,  Kent T. M. Fung,  Matthew Bashton,  Huezin Lim,  Lisa Jones,  Nefeli Karataraki,  Emily Winterman,  Cody Ashby,  Andishe Attarbaschi,  Yves Bertrand,  Jutta Bradtke,  Barbara Buldini,  G. A. Amos Burke,  Giovanni Cazzaniga,  Gudrun Gohring,  Hesta A. de Groot-Kruseman,  Claudia Haferlach,  Luca Lo Nigro,  Mayur Parihar,  Adriana Plesa,  Emma Seaford,  Edwin Sonneveld,  Sabine Strehl,  Vincent H. J. van der Velden,  Vikki Rand,  Stephen P. Hunger,  Christine J. Harrison,  Chris M. Bacon,  Frederik W. van Delft,  Mignon L. Loh,  John Moppett,  Josef Vormoor,  Brian A. Walker,  Anthony V. Moorman,  Lisa J. Russell.

Haematologica

Mass spectrometry imaging of endogenous metabolites in response to doxorubicin in a novel 3D osteosarcoma cell culture model

Ieva Palubeckaite,  Lucy Crooks,  David P. Smith,  Laura M. Cole,  Heijs Bram,  Christine Le Maitre,  Malcolm R. Clench,  Neil A. Cross.

Journal of Mass Spectrometry
Volume: 55, Issue: 4, Pages: e4461.

<i>CTNNB1</i> mutations are clonal in adamantinomatous craniopharyngioma

J. R. Apps,  C. Stache,  J. M. Gonzalez-Meljem,  A. Gutteridge,  J. Chalker,  T. S. Jacques,  T. Forshew,  A. Hölsken,  J. P. Martinez-Barbera.

Neuropathology and Applied Neurobiology
Volume: 46, Issue: 5, Pages: 510-514.

Adjuvant tyrosine kinase inhibitor therapy improves outcome for children and adolescents with acute lymphoblastic leukaemia who have an ABL-class fusion

Anthony V. Moorman,  Claire Schwab,  Emily Winterman,  Jerry Hancock,  Anna Castleton,  Michelle Cummins,  Brenda Gibson,  Nick Goulden,  Pam Kearns,  Beki James,  Amy A. Kirkwood,  Donna Lancaster,  Mabrouk Madi,  Andrew McMillan,  Jayashree Motwani,  Alice Norton,  Aengus O’Marcaigh,  Katharine Patrick,  Neha Bhatnagar,  Amrana Qureshi,  Deborah Richardson,  Simone Stokley,  Gordon Taylor,  Frederik W. van Delft,  John Moppett,  Christine J. Harrison,  Sujith Samarasinghe,  Ajay Vora.

British Journal of Haematology
Volume: 191, Issue: 5, Pages: 844-851.

Mass spectrometry imaging of endogenous metabolites in response to doxorubicin in a novel 3D osteosarcoma cell culture model

Ieva Palubeckaite,  Lucy Crooks,  David P. Smith,  Laura M. Cole,  Heijs Bram,  Christine Le Maitre,  Malcolm R. Clench,  Neil A. Cross.

Journal of Mass Spectrometry
Volume: 55, Issue: 4, Pages: e4461.

CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma

J. R. Apps,  C. Stache,  J. M. Gonzalez-Meljem,  A. Gutteridge,  J. Chalker,  T. S. Jacques,  T. Forshew,  A. Hölsken,  J. P. Martinez-Barbera.

Neuropathology and Applied Neurobiology
Volume: 46, Issue: 5, Pages: 510-514.

Embryonal precursors of Wilms tumor

Tim H. H. Coorens,  Taryn D. Treger,  Reem Al-Saadi,  Luiza Moore,  Maxine G. B. Tran,  Thomas J. Mitchell,  Suzanne Tugnait,  Christine Thevanesan,  Matthew D. Young,  Thomas R. W. Oliver,  Minou Oostveen,  Grace Collord,  Patrick S. Tarpey,  Alex Cagan,  Yvette Hooks,  Mark Brougham,  Ben C. Reynolds,  Giuseppe Barone,  John Anderson,  Mette Jorgensen,  G. A. Amos Burke,  Johannes Visser,  James C. Nicholson,  Naima Smeulders,  Imran Mushtaq,  Grant D. Stewart,  Peter J. Campbell,  David C. Wedge,  Iñigo Martincorena,  Dyanne Rampling,  Liz Hook,  Anne Y. Warren,  Nicholas Coleman,  Tanzina Chowdhury,  Neil Sebire,  Jarno Drost,  Kourosh Saeb-Parsy,  Michael R. Stratton,  Karin Straathof,  Kathy Pritchard-Jones,  Sam Behjati.

Science
Volume: 366, Issue: 6470, Pages: 1247-1251.

Trisomy 21 Driven Pro-Inflammatory Signalling in Fetal Bone Marrow May Play a Role in Perturbed B-Lymphopoiesis and Acute Lymphoblastic Leukemia of Down Syndrome

Sorcha Isabella O'Byrne,  Natalina Elliott,  Gemma Buck,  Siobhan Rice,  David O'Connor,  Jana Oswald,  Hannah Fuchs,  Ella-Mae Labbett,  Nicholas James Fordham,  Anindita Roy,  Irene Roberts.

Blood
Volume: 134, Issue: Supplement_1, Pages: 1206-1206.

A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations

Sally L. George,  Elisa Izquierdo,  James Campbell,  Eleni Koutroumanidou,  Paula Proszek,  Sabri Jamal,  Deborah Hughes,  Lina Yuan,  Lynley V. Marshall,  Fernando Carceller,  Julia C. Chisholm,  Sucheta Vaidya,  Henry Mandeville,  Paola Angelini,  Ajla Wasti,  Tomas Bexelius,  Khin Thway,  Susanne A. Gatz,  Matthew Clarke,  Bissan Al-Lazikani,  Giuseppe Barone,  John Anderson,  Deborah A. Tweddle,  David Gonzalez,  Brian A. Walker,  Jack Barton,  Sarita Depani,  Jessica Eze,  Saira W. Ahmed,  Lucas Moreno,  Andrew Pearson,  Janet Shipley,  Chris Jones,  Darren Hargrave,  Thomas S. Jacques,  Michael Hubank,  Louis Chesler.

European Journal of Cancer
Volume: 121, Pages: 224-235.

Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs

Sorcha O’Byrne,  Natalina Elliott,  Siobhan Rice,  Gemma Buck,  Nicholas Fordham,  Catherine Garnett,  Laura Godfrey,  Nicholas T. Crump,  Gary Wright,  Sarah Inglott,  Peng Hua,  Bethan Psaila,  Benjamin Povinelli,  David J. H. F. Knapp,  Antonio Agraz-Doblas,  Clara Bueno,  Ignacio Varela,  Phillip Bennett,  Hashem Koohy,  Suzanne M. Watt,  Anastasios Karadimitris,  Adam J. Mead,  Phillip Ancliff,  Paresh Vyas,  Pablo Menendez,  Thomas A. Milne,  Irene Roberts,  Anindita Roy.

Blood
Volume: 134, Issue: 13, Pages: 1059-1071.

Overall Survival in Malignant Glioma Is Significantly Prolonged by Neurosurgical Delivery of Etoposide and Temozolomide from a Thermo-Responsive Biodegradable Paste

Stuart J. Smith,  Betty M. Tyler,  Toby Gould,  Gareth J. Veal,  Noah Gorelick,  Jonathan Rowlinson,  Riccardo Serra,  Alison Ritchie,  Phillip Berry,  Annette Otto,  John Choi,  Nicolas Skuli,  Maria Estevez-Cebrero,  Kevin M. Shakesheff,  Henry Brem,  Richard G. Grundy,  Ruman Rahman.

Clinical Cancer Research
Volume: 25, Issue: 16, Pages: 5094-5106.

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome

Maurice Labuhn,  Kelly Perkins,  Sören Matzk,  Leila Varghese,  Catherine Garnett,  Elli Papaemmanuil,  Marlen Metzner,  Alison Kennedy,  Vyacheslav Amstislavskiy,  Thomas Risch,  Raj Bhayadia,  David Samulowski,  David Cruz Hernandez,  Bilyana Stoilova,  Valentina Iotchkova,  Udo Oppermann,  Carina Scheer,  Kenichi Yoshida,  Adrian Schwarzer,  Jeffrey W. Taub,  John D. Crispino,  Mitchell J. Weiss,  Yasuhide Hayashi,  Takashi Taga,  Etsuro Ito,  Seishi Ogawa,  Dirk Reinhardt,  Marie-Laure Yaspo,  Peter J. Campbell,  Irene Roberts,  Stefan N. Constantinescu,  Paresh Vyas,  Dirk Heckl,  Jan-Henning Klusmann.

Cancer Cell
Volume: 36, Issue: 2, Pages: 123-138.e10.

Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes

Tanvi Sharma,  Edward C. Schwalbe,  Daniel Williamson,  Martin Sill,  Volker Hovestadt,  Martin Mynarek,  Stefan Rutkowski,  Giles W. Robinson,  Amar Gajjar,  Florence Cavalli,  Vijay Ramaswamy,  Michael D. Taylor,  Janet C. Lindsey,  Rebecca M. Hill,  Natalie Jäger,  Andrey Korshunov,  Debbie Hicks,  Simon Bailey,  Marcel Kool,  Lukas Chavez,  Paul A. Northcott,  Stefan M. Pfister,  Steven C. Clifford.

Acta Neuropathologica
Volume: 138, Issue: 2, Pages: 309-326.

MIR-128A AND MIR-130B DETERMINE LINEAGE CHOICE AND LEUKEMIA-PROPAGATING CELL IDENTITY IN MLL-AF4+ ACUTE LEUKEMIA

Katrin Ottersbach,  Camille Malouf,  Franziska Sahm,  Sophie-Luise Landua.

Experimental Hematology
Volume: 76, Pages: S81.

A role for ABCB1 in prognosis, invasion and drug resistance in ependymoma

Durgagauri H. Sabnis,  Lisa C. D. Storer,  Jo-Fen Liu,  Hannah K. Jackson,  J. P. Kilday,  Richard G. Grundy,  Ian D. Kerr,  Beth Coyle.

Scientific Reports
Volume: 9, Issue: 1, Pages: 10290.

Sporadic and endemic Burkitt lymphoma have frequent FOXO1 mutations but distinct hotspots in the AKT recognition motif

Peixun Zhou,  Alex E. Blain,  Alexander M. Newman,  Masood Zaka,  George Chagaluka,  Filbert R. Adlar,  Ugonna T. Offor,  Casey Broadbent,  Lewis Chaytor,  Amber Whitehead,  Amy Hall,  Hettie O’Connor,  Susan Van Noorden,  Irvin Lampert,  Simon Bailey,  Elizabeth Molyneux,  Chris M. Bacon,  Simon Bomken,  Vikki Rand.

Blood Advances
Volume: 3, Issue: 14, Pages: 2118-2127.

A <i>C19MC-</i>LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor

Patrick Sin-Chan,  Iqra Mumal,  Tannu Suwal,  Ben Ho,  Xiaolian Fan,  Irtisha Singh,  Yuchen Du,  Mei Lu,  Neilket Patel,  Jonathon Torchia,  Dean Popovski,  Maryam Fouladi,  Paul Guilhamon,  Jordan R. Hansford,  Sarah Leary,  Lindsey M. Hoffman,  Jean M. Mulcahy Levy,  Alvaro Lassaletta,  Palma Solano-Paez,  Eloy Rivas,  Alyssa Reddy,  G. Yancey Gillespie,  Nalin Gupta,  Timothy E. Van Meter,  Hideo Nakamura,  Tai-Tong Wong,  Young-Shin Ra,  Seung-Ki Kim,  Luca Massimi,  Richard G. Grundy,  Jason Fangusaro,  Donna Johnston,  Jennifer Chan,  Lucie Lafay-Cousin,  Eugene I. Hwang,  Yin Wang,  Daniel Catchpoole,  Jean Michaud,  Benjamin Ellezam,  Ramya Ramanujachar,  Holly Lindsay,  Michael D. Taylor,  Cynthia E. Hawkins,  Eric Bouffet,  Nada Jabado,  Sheila K. Singh,  Claudia L. Kleinman,  Dalia Barsyte-Lovejoy,  Xiao-Nan Li,  Peter B. Dirks,  Charles Y. Lin,  Stephen C. Mack,  Jeremy N. Rich,  Annie Huang.

Cancer Cell
Volume: 36, Issue: 1, Pages: 51-67.e7.

PF153 MLL-AF4 CAUSES ABERRANT UPREGULATION OF PROM1 (CD133) IN ACUTE LYMPHOBLASTIC LEUKEMIA BY CONTROLLING ENHANCER-PROMOTER INTERACTIONS

L. Godfrey,  S. O’Byrne,  N. T. Crump,  I.-J. Lau,  R. Thorne,  N. Elliott,  G. Buck,  S. Rice,  C. Connor,  R. Thomas,  D. Cheng,  P. Ancliff,  S. Inglott,  I. Roberts,  A. Roy,  T. A. Milne.

HemaSphere
Volume: 3, Issue: S1, Pages: 29.

c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism

Ashirwad Merve,  Xinyu Zhang,  Nicola Pomella,  Serena Acquati,  Joerg D. Hoeck,  Anaelle Dumas,  Gabriel Rosser,  Yichen Li,  Jennie Jeyapalan,  Silvia Vicenzi,  Qianhai Fan,  Zeng Jie Yang,  Arianna Sabò,  Denise Sheer,  Axel Behrens,  Silvia Marino.

Acta Neuropathologica Communications
Volume: 7, Issue: 1, Pages: 95.

Identification of new Wilms tumour predisposition genes: an exome sequencing study

Shazia Mahamdallie,  Shawn Yost,  Emma Poyastro-Pearson,  Esty Holt,  Anna Zachariou,  Sheila Seal,  Anna Elliott,  Matthew Clarke,  Margaret Warren-Perry,  Sandra Hanks,  John Anderson,  Simon Bomken,  Trevor Cole,  Roula Farah,  Rhoikos Furtwaengler,  Adam Glaser,  Richard Grundy,  James Hayden,  Steve Lowis,  Frédéric Millot,  James Nicholson,  Milind Ronghe,  Jane Skeen,  Denise Williams,  Daniel Yeomanson,  Elise Ruark,  Nazneen Rahman.

The Lancet Child & Adolescent Health
Volume: 3, Issue: 5, Pages: 322-331.

Single-cell analysis identifies CRLF2 rearrangements as both early and late events in Down syndrome and non-Down syndrome acute lymphoblastic leukaemia

N. Potter,  L. Jones,  H. Blair,  S. Strehl,  C. J. Harrison,  M. Greaves,  L. Kearney,  L. J. Russell.

Leukemia
Volume: 33, Issue: 4, Pages: 893-904.

Outcomes of patients with childhood B-cell precursor acute lymphoblastic leukaemia with late bone marrow relapses: long-term follow-up of the ALLR3 open-label randomised trial

Catriona Parker,  Shekhar Krishnan,  Lina Hamadeh,  Julie A. E. Irving,  Roland P. Kuiper,  Tamas Révész,  Peter Hoogerbrugge,  Jeremy Hancock,  Rosemary Sutton,  Anthony V. Moorman,  Vaskar Saha.

The Lancet. Haematology
Volume: 6, Issue: 4, Pages: e204-e216.

Trypsin-encoding PRSS1-PRSS2 variations influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report

Benjamin O. Wolthers,  Thomas L. Frandsen,  Chirag J. Patel,  Rachid Abaji,  Andishe Attarbaschi,  Shlomit Barzilai,  Antonella Colombini,  Gabriele Escherich,  Marie Grosjean,  Maja Krajinovic,  Eric Larsen,  Der-Cherng Liang,  Anja Möricke,  Kirsten K. Rasmussen,  Sujith Samarasinghe,  Lewis B. Silverman,  Inge M. van der Sluis,  Martin Stanulla,  Morten Tulstrup,  Rachita Yadav,  Wenjian Yang,  Ester Zapotocka,  Ramneek Gupta,  Kjeld Schmiegelow,  Ponte di Legno toxicity working group.

Haematologica
Volume: 104, Issue: 3, Pages: 556-563.

Outcomes of non-anaplastic stage III and ‘inoperable’ Wilms tumour treated in the UKW3 trial

Sabine Irtan,  Boo Messahel,  Veronica Moroz,  Roger E. Taylor,  Richard Grundy,  Anna Kelsey,  Gordan Vujanic,  Kathy Pritchard-Jones.

Radiotherapy and Oncology
Volume: 131, Pages: 1-7.

The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL

Kim R. Kampen,  Sergey O. Sulima,  Benno Verbelen,  Tiziana Girardi,  Stijn Vereecke,  Gianmarco Rinaldi,  Jelle Verbeeck,  Joyce Op de Beeck,  Anne Uyttebroeck,  Jules P. P. Meijerink,  Anthony V. Moorman,  Christine J. Harrison,  Pieter Spincemaille,  Jan Cools,  David Cassiman,  Sarah-Maria Fendt,  Pieter Vermeersch,  Kim De Keersmaecker.

Leukemia
Volume: 33, Issue: 2, Pages: 319-332.

The journey to CAR T cell therapy: the pediatric and young adult experience with relapsed or refractory B-ALL

George Hucks,  Susan R. Rheingold.

Blood Cancer Journal
Volume: 9, Issue: 2, Pages: 10.

Validation of the United Kingdom copy-number alteration classifier in 3239 children with B-cell precursor ALL

Lina Hamadeh,  Amir Enshaei,  Claire Schwab,  Cristina N. Alonso,  Andishe Attarbaschi,  Gisela Barbany,  Monique L. den Boer,  Judith M. Boer,  Marcin Braun,  Luciano Dalla Pozza,  Sarah Elitzur,  Mariana Emerenciano,  Larisa Fechina,  Maria Sara Felice,  Eva Fronkova,  Irén Haltrich,  Mats M. Heyman,  Keizo Horibe,  Toshihiko Imamura,  Marta Jeison,  Gábor Kovács,  Roland P. Kuiper,  Wojciech Mlynarski,  Karin Nebral,  Ingegerd Ivanov Öfverholm,  Agata Pastorczak,  Rob Pieters,  Henriett Piko,  Maria S. Pombo-de-Oliveira,  Patricia Rubio,  Sabine Strehl,  Jan Stary,  Rosemary Sutton,  Jan Trka,  Grigory Tsaur,  Nicola Venn,  Ajay Vora,  Mio Yano,  Christine J. Harrison,  Anthony V. Moorman,  International BFM Study Group.

Blood Advances
Volume: 3, Issue: 2, Pages: 148-157.

Non-secreting pituitary tumours characterised by enhanced expression of YAP/TAZ

Paraskevi Xekouki,  Emily J. Lodge,  Jakob Matschke,  Alice Santambrogio,  John R. Apps,  Ariane Sharif,  Thomas S. Jacques,  Simon Aylwin,  Vincent Prevot,  Ran Li,  Jörg Flitsch,  Stefan R. Bornstein,  Marily Theodoropoulou,  Cynthia L. Andoniadou.

Endocrine-Related Cancer
Volume: 26, Issue: 1, Pages: 215-225.

Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor

Andrea Biondi,  Gunnar Cario,  Paola De Lorenzo,  Anders Castor,  Valentino Conter,  Veronica Leoni,  Virginie Gandemer,  Rob Pieters,  Jan Stary,  Gabriele Escherich,  Myriam Campbell,  Andishe Attarbaschi,  Chi-Kong Li,  Ajay Vora,  Jutta Bradtke,  Vaskar Saha,  Maria Grazia Valsecchi,  Martin Schrappe.

Haematologica
Volume: 104, Issue: 1, Pages: e13-e16.

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

Gloria Milani,  Filip Matthijssens,  Wouter Van Loocke,  Kaat Durinck,  Juliette Roels,  Sofie Peirs,  Morgan Thénoz,  Tim Pieters,  Lindy Reunes,  Beatrice Lintermans,  Niels Vandamme,  Tim Lammens,  Nadine Van Roy,  Filip Van Nieuwerburgh,  Dieter Deforce,  Claire Schwab,  Susana Raimondi,  Luciano Dalla Pozza,  Andrew J. Carroll III,  Barbara De Moerloose,  Yves Benoit,  Steven Goossens,  Geert Berx,  Christine J. Harrison,  Giuseppe Basso,  Hélène Cavé,  Rosemary Sutton,  Vahid Asnafi,  Jules Meijerink,  Charles Mullighan,  Mignon Loh,  Pieter Van Vlierberghe.

British Journal of Haematology
Volume: 185, Issue: 1, Pages: 169-174.

Impact of dose and duration of therapy on dexamethasone pharmacokinetics in childhood acute lymphoblastic leukaemia—a report from the UKALL 2011 trial

Rosanna K. Jackson,  Martina Liebich,  Philip Berry,  Julie Errington,  Jizhong Liu,  Catriona Parker,  John Moppett,  Sujith Samarasinghe,  Rachael Hough,  Clare Rowntree,  Nick J. Goulden,  Ajay Vora,  Pamela R. Kearns,  Vaskar Saha,  Georg Hempel,  Julie A.E. Irving,  Gareth J. Veal.

European Journal of Cancer
Volume: 120, Pages: 75-85.

The diagnostic accuracy and clinical utility of pediatric renal tumor biopsy: Report of the UK experience in the SIOP UK WT 2001 trial

Thomas J. Jackson,  Richard D. Williams,  Jesper Brok,  Tanzina Chowdhury,  Milind Ronghe,  Mark Powis,  Kathy Pritchard-Jones,  Gordan M. Vujanic,  on behalf of the Children's Cancer and Leukaemia Group (CCLG) Renal Tumours Group.

Pediatric Blood & Cancer
Volume: 66, Issue: 6, Pages: e27627.

A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations

Sally L. George,  Elisa Izquierdo,  James Campbell,  Eleni Koutroumanidou,  Paula Proszek,  Sabri Jamal,  Deborah Hughes,  Lina Yuan,  Lynley V. Marshall,  Fernando Carceller,  Julia C. Chisholm,  Sucheta Vaidya,  Henry Mandeville,  Paola Angelini,  Ajla Wasti,  Tomas Bexelius,  Khin Thway,  Susanne A. Gatz,  Matthew Clarke,  Bissan Al-Lazikani,  Giuseppe Barone,  John Anderson,  Deborah A. Tweddle,  David Gonzalez,  Brian A. Walker,  Jack Barton,  Sarita Depani,  Jessica Eze,  Saira W. Ahmed,  Lucas Moreno,  Andrew Pearson,  Janet Shipley,  Chris Jones,  Darren Hargrave,  Thomas S. Jacques,  Michael Hubank,  Louis Chesler.

European Journal of Cancer
Volume: 121, Pages: 224-235.

SH2B3 inactivation through CN-LOH 12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain

Paul B. Sinclair,  Sarra Ryan,  Matthew Bashton,  Shaun Hollern,  Rebecca Hanna,  Marian Case,  Edward C. Schwalbe,  Claire J. Schwab,  Ruth E. Cranston,  Brian D. Young,  Julie A. E. Irving,  Ajay J. Vora,  Anthony V. Moorman,  Christine J. Harrison.

Leukemia
Volume: 33, Issue: 8, Pages: 1881-1894.

Non-secreting pituitary tumours characterised by enhanced expression of YAP/TAZ

Paraskevi Xekouki,  Emily J Lodge,  Jakob Matschke,  Alice Santambrogio,  John R Apps,  Ariane Sharif,  Thomas S Jacques,  Simon Aylwin,  Vincent Prevot,  Ran Li,  Jörg Flitsch,  Stefan R Bornstein,  Marily Theodoropoulou,  Cynthia L Andoniadou.

Endocrine-Related Cancer
Volume: 26, Issue: 1, Pages: 215-225.

Correction to: c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism

Ashirwad Merve,  Xinyu Zhang,  Nicola Pomella,  Serena Acquati,  Joerg D. Hoeck,  Anaelle Dumas,  Gabriel Rosser,  Yichen Li,  Jennie Jeyapalan,  Silvia Vicenzi,  Qianhai Fan,  Zeng Jie Yang,  Arianna Sabò,  Denise Sheer,  Axel Behrens,  Silvia Marino.

Acta Neuropathologica Communications
Volume: 7, Issue: 1, Pages: 179.

Dual blockade of the PI3K/Akt/mTOR pathway inhibits posttransplant Epstein-Barr virus B cell lymphomas and promotes allograft survival

Adam X. Sang,  Marla C. McPherson,  Geoffrey T. Ivison,  Xiumei Qu,  Joseph Rigdon,  Carlos O. Esquivel,  Sheri M. Krams,  Olivia M. Martinez.

American Journal of Transplantation
Volume: 19, Issue: 5, Pages: 1305-1314.

Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk

Jayaram Vijayakrishnan,  Maoxiang Qian,  James B. Studd,  Wenjian Yang,  Ben Kinnersley,  Philip J. Law,  Peter Broderick,  Elizabeth A. Raetz,  James Allan,  Ching-Hon Pui,  Ajay Vora,  William E. Evans,  Anthony Moorman,  Allen Yeoh,  Wentao Yang,  Chunliang Li,  Claus R. Bartram,  Charles G. Mullighan,  Martin Zimmerman,  Stephen P. Hunger,  Martin Schrappe,  Mary V. Relling,  Martin Stanulla,  Mignon L. Loh,  Richard S. Houlston,  Jun J. Yang.

Nature Communications
Volume: 10, Issue: 1, Pages: 5348.

The effect of preoperative chemotherapy on histological subtyping and staging of Wilms tumors: The United Kingdom Children's Cancer Study Group (UKCCSG) Wilms tumor trial 3 (UKW3) experience

Gordan M. Vujanic,  Ellen D'Hooghe,  Sergey D. Popov,  Neil J. Sebire,  Anna Kelsey.

Pediatric Blood & Cancer
Volume: 66, Issue: 3, Pages: e27549.

The role of solute carrier (SLC) transporters in actinomycin D pharmacokinetics in paediatric cancer patients

Hannah Yejin Kim,  Gareth J. Veal,  Fanfan Zhou,  Alan V. Boddy.

European Journal of Clinical Pharmacology
Volume: 74, Issue: 12, Pages: 1575-1584.

Somatic <i>TP53</i> Mutations Are Detectable in Circulating Tumor DNA from Children with Anaplastic Wilms Tumors

Taryn D. Treger,  Tasnim Chagtai,  Robert Butcher,  George D. Cresswell,  Reem Al-Saadi,  Jesper Brok,  Richard D. Williams,  Chrissy Roberts,  Nicholas M. Luscombe,  Kathy Pritchard Jones,  William Mifsud.

Translational Oncology
Volume: 11, Issue: 6, Pages: 1301-1306.

Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial

Tobias Goschzik,  Edward C Schwalbe,  Debbie Hicks,  Amanda Smith,  Anja zur Muehlen,  Dominique Figarella-Branger,  François Doz,  Stefan Rutkowski,  Birgitta Lannering,  Torsten Pietsch,  Steven C Clifford.

The Lancet Oncology
Volume: 19, Issue: 12, Pages: 1602-1616.

Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010): a prospective, intergroup, open-label, single-arm clinical trial

Andrea Biondi,  Virginie Gandemer,  Paola De Lorenzo,  Gunnar Cario,  Myriam Campbell,  Anders Castor,  Rob Pieters,  André Baruchel,  Ajay Vora,  Veronica Leoni,  Jan Stary,  Gabriele Escherich,  Chi-Kong Li,  Giovanni Cazzaniga,  Hélène Cavé,  Jutta Bradtke,  Valentino Conter,  Vaskar Saha,  Martin Schrappe,  Maria Grazia Valsecchi.

The Lancet. Haematology
Volume: 5, Issue: 12, Pages: e641-e652.

Single-cell analysis identifies CRLF2 rearrangements as both early and late events in Down syndrome and non-Down syndrome acute lymphoblastic leukaemia

N. Potter,  L. Jones,  H. Blair,  S. Strehl,  C. J. Harrison,  M. Greaves,  L. Kearney,  L. J. Russell.

Leukemia
Volume: 33, Pages: 893-904.

Limitations of current in vitro models for testing the clinical potential of epigenetic inhibitors for treatment of pediatric ependymoma

Hazel Anne Rogers,  Rebecca Chapman,  Holly Kings,  Julie Allard,  Jodie Barron-Hastings,  Kristian W. Pajtler,  Martin Sill,  Stefan Pfister,  Richard Guy Grundy.

Oncotarget
Volume: 9, Issue: 92, Pages: 36530-36541.

The UMBRELLA SIOP–RTSG 2016 Wilms tumour pathology and molecular biology protocol

Gordan M. Vujanic,  Manfred Gessler,  Ariadne H. A. G. Ooms,  Paola Collini,  Aurore Coulomb-l’Hermine,  Ellen D’Hooghe,  Ronald R. de Krijger,  Daniela Perotti,  Kathy Pritchard-Jones,  Christian Vokuhl,  Marry M. van den Heuvel-Eibrink,  Norbert Graf.

Nature Reviews Urology
Volume: 15, Issue: 11, Pages: 693-701.

Prediction of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia

Rikke Linnemann Nielsen,  Benjamin Ole Wolthers,  Marianne Helenius,  Kjeld Schmiegelow,  Ramneek Gupta.

Oral presentation 13th International Conference on Genomics, Shenzen, China
Pages: 1.

Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012

Mareike Rasche,  Martin Zimmermann,  Lisa Borschel,  Jean-Pierre Bourquin,  Michael Dworzak,  Thomas Klingebiel,  Thomas Lehrnbecher,  Ursula Creutzig,  Jan-Henning Klusmann,  Dirk Reinhardt.

Leukemia
Volume: 32, Issue: 10, Pages: 2167.

The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia

Caroline L. Furness,  Marcela B. Mansur,  Victoria J. Weston,  Luca Ermini,  Frederik W. van Delft,  Sarah Jenkinson,  Rosemary Gale,  Christine J. Harrison,  Maria S. Pombo-de-Oliveira,  Marta Sanchez-Martin,  Adolfo A. Ferrando,  Pamela Kearns,  Ian Titley,  Anthony M. Ford,  Nicola E. Potter,  Mel Greaves.

Leukemia
Volume: 32, Issue: 9, Pages: 1984-1993.

Glutamate receptor d2 serum antibodies in pediatric opsoclonus myoclonus ataxia syndrome

Georgina Berridge,  David A. Menassa,  Teresa Moloney,  Patrick J. Waters,  Imogen Welding,  Selina Thomsen,  Sameer Zuberi,  Roman Fischer,  A. Radu Aricescu,  Michael Pike,  Russell C. Dale,  Benedikt Kessler,  Angela Vincent,  Ming Lim,  Sarosh R. Irani,  Bethan Lang.

Neurology
Volume: 91, Issue: 8.

Glutamate receptor d2 serum antibodies in pediatric opsoclonus myoclonus ataxia syndrome

Georgina Berridge,  David A. Menassa,  Teresa Moloney,  Patrick J. Waters,  Imogen Welding,  Selina Thomsen,  Sameer Zuberi,  Roman Fischer,  A. Radu Aricescu,  Michael Pike,  Russell C. Dale,  Benedikt Kessler,  Angela Vincent,  Ming Lim,  Sarosh R. Irani,  Bethan Lang.

Neurology
Volume: 91, Issue: 8, Pages: e714-e723.

Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours

Christopher D. Bennett,  Sarah E. Kohe,  Simrandip K. Gill,  Nigel P. Davies,  Martin Wilson,  Lisa C. D. Storer,  Timothy Ritzmann,  Simon M. L. Paine,  Ian S. Scott,  Ina Nicklaus-Wollenteit,  Daniel A. Tennant,  Richard G. Grundy,  Andrew C. Peet.

Scientific Reports
Volume: 8, Issue: 1, Pages: 11992.

Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas

Kristian W. Pajtler,  Ji Wen,  Martin Sill,  Tong Lin,  Wilda Orisme,  Bo Tang,  Jens-Martin Hübner,  Vijay Ramaswamy,  Sujuan Jia,  James D. Dalton,  Kelly Haupfear,  Hazel A. Rogers,  Chandanamali Punchihewa,  Ryan Lee,  John Easton,  Gang Wu,  Timothy A. Ritzmann,  Rebecca Chapman,  Lukas Chavez,  Fredrick A. Boop,  Paul Klimo,  Noah D. Sabin,  Robert Ogg,  Stephen C. Mack,  Brian D. Freibaum,  Hong Joo Kim,  Hendrik Witt,  David T. W. Jones,  Baohan Vo,  Amar Gajjar,  Stan Pounds,  Arzu Onar-Thomas,  Martine F. Roussel,  Jinghui Zhang,  J. Paul Taylor,  Thomas E. Merchant,  Richard Grundy,  Ruth G. Tatevossian,  Michael D. Taylor,  Stefan M. Pfister,  Andrey Korshunov,  Marcel Kool,  David W. Ellison.

Acta Neuropathologica
Volume: 136, Issue: 2, Pages: 211-226.

Mosaic-variegated aneuploidy syndrome mutation or haploinsufficiency in <i>Cep57</i> impairs tumor suppression

Khaled Aziz,  Cynthia J. Sieben,  Karthik B. Jeganathan,  Masakazu Hamada,  Brian A. Davies,  Raul O. Fierro Velasco,  Nazneen Rahman,  David J. Katzmann,  Jan M. van Deursen.

The Journal of Clinical Investigation
Volume: 128, Issue: 8, Pages: 3517-3534.

Relapse of Wilms' tumour and detection methods: a retrospective analysis of the 2001 Renal Tumour Study Group–International Society of Paediatric Oncology Wilms' tumour protocol database

Jesper Brok,  Marta Lopez-Yurda,  Harm V Tinteren,  Taryn D Treger,  Rhoikos Furtwängler,  Norbert Graf,  Christophe Bergeron,  Marry M van den Heuvel-Eibrink,  Kathy Pritchard-Jones,  Øystein E Olsen,  Beatriz de Camargo,  Arnauld Verschuur,  Filippo Spreafico.

The Lancet Oncology
Volume: 19, Issue: 8, Pages: 1072-1081.

TCRaß/CD3 disruption enables CD3-specific antileukemic T cell immunotherapy

Jane Rasaiyaah,  Christos Georgiadis,  Roland Preece,  Ulrike Mock,  Waseem Qasim.

JCI insight
Volume: 3, Issue: 13.

Prognostic impact of the absence of biallelic deletion at the TRG locus for pediatric patients with T-cell acute lymphoblastic leukemia treated on the Medical Research Council UK Acute Lymphoblastic Leukemia 2003 trial

Nadine Farah,  Amy A. Kirkwood,  Sunniyat Rahman,  Theresa Leon,  Sarah Jenkinson,  Rosemary E. Gale,  Katharine Patrick,  Jeremy Hancock,  Sujith Samarasinghe,  David C. Linch,  Anthony V. Moorman,  Nicholas Goulden,  Ajay Vora,  Marc R. Mansour.

Haematologica
Volume: 103, Issue: 7, Pages: e288-e292.

Circulating MicroRNA Biomarkers in Melanoma: Tools and Challenges in Personalised Medicine

Sophie L. Mumford,  Benjamin P. Towler,  Amy L. Pashler,  Onur Gilleard,  Yella Martin,  Sarah F. Newbury.

Biomolecules
Volume: 8, Issue: 2, Pages: 21.

Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target

John R. Apps,  Gabriela Carreno,  Jose Mario Gonzalez-Meljem,  Scott Haston,  Romain Guiho,  Julie E. Cooper,  Saba Manshaei,  Nital Jani,  Annett Hölsken,  Benedetta Pettorini,  Robert J. Beynon,  Deborah M. Simpson,  Helen C. Fraser,  Ying Hong,  Shirleen Hallang,  Thomas J. Stone,  Alex Virasami,  Andrew M. Donson,  David Jones,  Kristian Aquilina,  Helen Spoudeas,  Abhijit R. Joshi,  Richard Grundy,  Lisa C. D. Storer,  Márta Korbonits,  David A. Hilton,  Kyoko Tossell,  Selvam Thavaraj,  Mark A. Ungless,  Jesus Gil,  Rolf Buslei,  Todd Hankinson,  Darren Hargrave,  Colin Goding,  Cynthia L. Andoniadou,  Paul Brogan,  Thomas S. Jacques,  Hywel J. Williams,  Juan Pedro Martinez-Barbera.

Acta Neuropathologica
Volume: 135, Issue: 5, Pages: 757-777.

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Paul B. Sinclair,  Helen H. Blair,  Sarra L. Ryan,  Lars Buechler,  Joanna Cheng,  Jake Clayton,  Rebecca Hanna,  Shaun Hollern,  Zoe Hawking,  Matthew Bashton,  Claire J. Schwab,  Lisa Jones,  Lisa J. Russell,  Helen Marr,  Peter Carey,  Christina Halsey,  Olaf Heidenreich,  Anthony V. Moorman,  Christine J. Harrison.

Haematologica
Volume: 103, Issue: 4, Pages: 634-644.

Immunohistochemical evaluation of molecular radiotherapy target expression in neuroblastoma tissue

Jennifer E. Gains,  Neil J. Sebire,  Veronica Moroz,  Keith Wheatley,  Mark N. Gaze.

European Journal of Nuclear Medicine and Molecular Imaging
Volume: 45, Issue: 3, Pages: 402-411.

Metabolic profiling of the three neural derived embryonal pediatric tumors retinoblastoma, neuroblastoma and medulloblastoma, identifies distinct metabolic profiles

Sarah E. Kohe,  Christopher D. Bennett,  Simrandip K. Gill,  Martin Wilson,  Carmel McConville,  Andrew C. Peet.

Oncotarget
Volume: 9, Issue: 13, Pages: 11336-11351.

Metabolite Levels in Paediatric Brain Tumours Correlate with Histological Features

Eleni Orphanidou-Vlachou,  Sarah E. Kohe,  Marie-Anne Brundler,  Lesley MacPherson,  Yu Sun,  Nigel Davies,  Martin Wilson,  Xiaoyan Pan,  Theodoros N. Arvanitis,  Richard G. Grundy,  Andrew C. Peet.

Pathobiology
Volume: 85, Issue: 3, Pages: 157-168.

Comprehensive molecular characterisation of epilepsy-associated glioneuronal tumours

Thomas J. Stone,  Angus Keeley,  Alex Virasami,  William Harkness,  Martin Tisdall,  Elisa Izquierdo Delgado,  Alice Gutteridge,  Tony Brooks,  Mark Kristiansen,  Jane Chalker,  Lisa Wilkhu,  William Mifsud,  John Apps,  Maria Thom,  Mike Hubank,  Tim Forshew,  J. Helen Cross,  Darren Hargrave,  Jonathan Ham,  Thomas S. Jacques.

Acta Neuropathologica
Volume: 135, Issue: 1, Pages: 115-129.

Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia

David O'Connor,  Amir Enshaei,  Jack Bartram,  Jeremy Hancock,  Christine J. Harrison,  Rachael Hough,  Sujith Samarasinghe,  Claire Schwab,  Ajay Vora,  Rachel Wade,  John Moppett,  Anthony V. Moorman,  Nick Goulden.

Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Volume: 36, Issue: 1, Pages: 34-43.

Immunohistochemical evaluation of molecular radiotherapy target expression in neuroblastoma tissue

Jennifer E. Gains,  Neil J. Sebire,  Veronica Moroz,  Keith Wheatley,  Mark N. Gaze.

European Journal of Nuclear Medicine and Molecular Imaging
Volume: 45, Issue: 3, Pages: 402-411.

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Paul B. Sinclair,  Helen H. Blair,  Sarra L. Ryan,  Lars Buechler,  Joanna Cheng,  Jake Clayton,  Rebecca Hanna,  Shaun Hollern,  Zoe Hawking,  Matthew Bashton,  Claire J. Schwab,  Lisa Jones,  Lisa J. Russell,  Helen Marr,  Peter Carey,  Christina Halsey,  Olaf Heidenreich,  Anthony V. Moorman,  Christine J. Harrison.

Haematologica
Volume: 103, Issue: 4, Pages: 634-644.

Irinotecan for relapsed Wilms tumor in pediatric patients: SIOP experience and review of the literature—A report from the SIOP Renal Tumor Study Group

Janna A. Hol,  Marry M. van den Heuvel-Eibrink,  Norbert Graf,  Kathy Pritchard-Jones,  Jesper Brok,  Harm van Tinteren,  Lisa Howell,  Arnauld Verschuur,  Christophe Bergeron,  Leo Kager,  Serena Catania,  Filippo Spreafico,  Annelies M. C. Mavinkurve-Groothuis.

Pediatric Blood & Cancer
Volume: 65, Issue: 2, Pages: e26849.

RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins

Gail Anderson,  Nancy Mackay,  Kathryn Gilroy,  Jodie Hay,  Gillian Borland,  Alma McDonald,  Margaret Bell,  Siti Ayuni Hassanudin,  Ewan Cameron,  James C. Neil,  Anna Kilbey.

Journal of Cellular Biochemistry
Volume: 119, Issue: 3, Pages: 2750-2762.

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

Jayaram Vijayakrishnan,  James Studd,  Peter Broderick,  Ben Kinnersley,  Amy Holroyd,  Philip J. Law,  Rajiv Kumar,  James M. Allan,  Christine J. Harrison,  Anthony V. Moorman,  Ajay Vora,  Eve Roman,  Sivaramakrishna Rachakonda,  Sally E. Kinsey,  Eamonn Sheridan,  Pamela D. Thompson,  Julie A. Irving,  Rolf Koehler,  Per Hoffmann,  Markus M. Nöthen,  Stefanie Heilmann-Heimbach,  Karl-Heinz Jöckel,  Douglas F. Easton,  Paul D. P. Pharaoh,  Alison M. Dunning,  Julian Peto,  Frederico Canzian,  Anthony Swerdlow,  Rosalind A. Eeles,  ZSofia Kote-Jarai,  Kenneth Muir,  Nora Pashayan,  PRACTICAL Consortium,  Mel Greaves,  Martin Zimmerman,  Claus R. Bartram,  Martin Schrappe,  Martin Stanulla,  Kari Hemminki,  Richard S. Houlston.

Nature Communications
Volume: 9, Issue: 1, Pages: 1340.

Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies

Giovanni Cazzaniga,  Paola De Lorenzo,  Julia Alten,  Silja Röttgers,  Jeremy Hancock,  Vaskar Saha,  Anders Castor,  Hans O. Madsen,  Virginie Gandemer,  Hélène Cavé,  Veronica Leoni,  Rolf Köhler,  Giulia M. Ferrari,  Kirsten Bleckmann,  Rob Pieters,  Vincent van der Velden,  Jan Stary,  Jan Zuna,  Gabriele Escherich,  Udo Zur Stadt,  Maurizio Aricò,  Valentino Conter,  Martin Schrappe,  Maria Grazia Valsecchi,  Andrea Biondi.

Haematologica
Volume: 103, Issue: 1, Pages: 107-115.

Comprehensive molecular characterisation of epilepsy-associated glioneuronal tumours

Thomas J. Stone,  Angus Keeley,  Alex Virasami,  William Harkness,  Martin Tisdall,  Elisa Izquierdo Delgado,  Alice Gutteridge,  Tony Brooks,  Mark Kristiansen,  Jane Chalker,  Lisa Wilkhu,  William Mifsud,  John Apps,  Maria Thom,  Mike Hubank,  Tim Forshew,  J. Helen Cross,  Darren Hargrave,  Jonathan Ham,  Thomas S. Jacques.

Acta Neuropathologica
Volume: 135, Issue: 1, Pages: 115-129.

The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells

Eleanor M. O’Brien,  Joanna L. Selfe,  Ana Sofia Martins,  Zoë S. Walters,  Janet M. Shipley.

BMC Cancer
Volume: 18, Issue: 1, Pages: 217.

The genetic basis and cell of origin of mixed phenotype acute leukaemia

Thomas B. Alexander,  Zhaohui Gu,  Ilaria Iacobucci,  Kirsten Dickerson,  John K. Choi,  Beisi Xu,  Debbie Payne-Turner,  Hiroki Yoshihara,  Mignon L. Loh,  John Horan,  Barbara Buldini,  Giuseppe Basso,  Sarah Elitzur,  Valerie de Haas,  C. Michel Zwaan,  Allen Yeoh,  Dirk Reinhardt,  Daisuke Tomizawa,  Nobutaka Kiyokawa,  Tim Lammens,  Barbara De Moerloose,  Daniel Catchpoole,  Hiroki Hori,  Anthony Moorman,  Andrew S. Moore,  Ondrej Hrusak,  Soheil Meshinchi,  Etan Orgel,  Meenakshi Devidas,  Michael Borowitz,  Brent Wood,  Nyla A. Heerema,  Andrew Carrol,  Yung-Li Yang,  Malcolm A. Smith,  Tanja M. Davidsen,  Leandro C. Hermida,  Patee Gesuwan,  Marco A. Marra,  Yussanne Ma,  Andrew J. Mungall,  Richard A. Moore,  Steven J. M. Jones,  Marcus Valentine,  Laura J. Janke,  Jeffrey E. Rubnitz,  Ching-Hon Pui,  Liang Ding,  Yu Liu,  Jinghui Zhang,  Kim E. Nichols,  James R. Downing,  Xueyuan Cao,  Lei Shi,  Stanley Pounds,  Scott Newman,  Deqing Pei,  Jaime M. Guidry Auvil,  Daniela S. Gerhard,  Stephen P. Hunger,  Hiroto Inaba,  Charles G. Mullighan.

Nature
Volume: 562, Issue: 7727, Pages: 373-379.

Abstracts

No authors found.

British Journal of Haematology
Volume: 182, Issue: S1, Pages: 5-109.

RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins

Gail Anderson,  Nancy Mackay,  Kathryn Gilroy,  Jodie Hay,  Gillian Borland,  Alma McDonald,  Margaret Bell,  Siti Ayuni Hassanudin,  Ewan Cameron,  James C. Neil,  Anna Kilbey.

Journal of Cellular Biochemistry
Volume: 119, Issue: 3, Pages: 2750-2762.

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

Elisa Izquierdo,  Lina Yuan,  Sally George,  Michael Hubank,  Chris Jones,  Paula Proszek,  Janet Shipley,  Susanne A. Gatz,  Caedyn Stinson,  Andrew S. Moore,  Steven C. Clifford,  Debbie Hicks,  Janet C. Lindsey,  Rebecca M. Hill,  Thomas S. Jacques,  Jane Chalker,  Khin Thway,  Simon O’Connor,  Lynley Marshall,  Lucas Moreno,  Andrew Pearson,  Louis Chesler,  Brian A. Walker,  David Gonzalez De Castro.

Oncotarget
Volume: 8, Issue: 67, Pages: 112036-112050.

Transcriptomic analysis in pediatric spinal ependymoma reveals distinct molecular signatures

Anbarasu Lourdusamy,  Li Z. Luo,  Lisa CD Storer,  Kenneth J. Cohen,  Linda Resar,  Richard G. Grundy.

Oncotarget
Volume: 8, Issue: 70, Pages: 115570-115581.

Molecular and Functional Characterization of Disease-Propagating Stem Cells in Juvenile Myelomonocytic Leukemia

Eleni Louka,  Benjamin Povinelli,  Alba Rodriguez-Meira,  Gemma Buck,  Angela Hamblin,  Christopher Booth,  Anindita Roy,  Natalina Elliott,  Deena Iskander,  Josu de la Fuente,  Nicholas James Fordham,  Sorcha Isabella Obyrne,  Sarah Inglott,  Anupama Gopala Rao,  Irene Roberts,  Adam J. Mead.

Blood
Volume: 130, Issue: Suppl 1, Pages: 379-379.

Common Genetic Variants in Trypsin Regulating Genes Are Associated with AsparAginase-Associated Pancreatitis in Children with Acute Lymphoblastic Leukemia: A Ponte Di Legno Toxicity Working Group Study

Benjamin Ole Wolthers,  Thomas Leth Frandsen,  Andishe Attarbaschi,  Shlomit Barzilai,  Antonella Colombini,  Gabriele Escherich,  Marie Grosjean,  Ramneek Gupta,  Der-Cherng Liang,  Anja Moricke,  Chirag J. Patel,  Kirsten K. Rasmussen,  Sujith Samarasinghe,  Inge M. Van Der Sluis,  Martin Stanulla,  Morten Tulstrup,  Ester Zapotocka,  Kjeld Schmiegelow.

Blood
Volume: 130, Issue: Suppl 1, Pages: 885-885.

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

Elisa Izquierdo,  Lina Yuan,  Sally George,  Michael Hubank,  Chris Jones,  Paula Proszek,  Janet Shipley,  Susanne A. Gatz,  Caedyn Stinson,  Andrew S. Moore,  Steven C. Clifford,  Debbie Hicks,  Janet C. Lindsey,  Rebecca M. Hill,  Thomas S. Jacques,  Jane Chalker,  Khin Thway,  Simon O’Connor,  Lynley Marshall,  Lucas Moreno,  Andrew Pearson,  Louis Chesler,  Brian A. Walker,  David Gonzalez De Castro.

Oncotarget
Volume: 8, Issue: 67, Pages: 112036-112050.

Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma

Jose Mario Gonzalez-Meljem,  Scott Haston,  Gabriela Carreno,  John R. Apps,  Sara Pozzi,  Christina Stache,  Grace Kaushal,  Alex Virasami,  Leonidas Panousopoulos,  Seyedeh Neda Mousavy-Gharavy,  Ana Guerrero,  Mamunur Rashid,  Nital Jani,  Colin R. Goding,  Thomas S. Jacques,  David J. Adams,  Jesus Gil,  Cynthia L. Andoniadou,  Juan Pedro Martinez-Barbera.

Nature Communications
Volume: 8, Issue: 1, Pages: 1819.

Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma

Jose Mario Gonzalez-Meljem,  Scott Haston,  Gabriela Carreno,  John R. Apps,  Sara Pozzi,  Christina Stache,  Grace Kaushal,  Alex Virasami,  Leonidas Panousopoulos,  Seyedeh Neda Mousavy-Gharavy,  Ana Guerrero,  Mamunur Rashid,  Nital Jani,  Colin R. Goding,  Thomas S. Jacques,  David J. Adams,  Jesus Gil,  Cynthia L. Andoniadou,  Juan Pedro Martinez-Barbera.

Nature Communications
Volume: 8, Issue: 1, Pages: 1819.

Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures

E. C. Schwalbe,  D. Hicks,  G. Rafiee,  M. Bashton,  H. Gohlke,  A. Enshaei,  S. Potluri,  J. Matthiesen,  M. Mather,  P. Taleongpong,  R. Chaston,  A. Silmon,  A. Curtis,  J. C. Lindsey,  S. Crosier,  A. J. Smith,  T. Goschzik,  F. Doz,  S. Rutkowski,  B. Lannering,  T. Pietsch,  S. Bailey,  D. Williamson,  S. C. Clifford.

Scientific Reports
Volume: 7, Issue: 1, Pages: 13421.

Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures

E. C. Schwalbe,  D. Hicks,  G. Rafiee,  M. Bashton,  H. Gohlke,  A. Enshaei,  S. Potluri,  J. Matthiesen,  M. Mather,  P. Taleongpong,  R. Chaston,  A. Silmon,  A. Curtis,  J. C. Lindsey,  S. Crosier,  A. J. Smith,  T. Goschzik,  F. Doz,  S. Rutkowski,  B. Lannering,  T. Pietsch,  S. Bailey,  D. Williamson,  S. C. Clifford.

Scientific Reports
Volume: 7, Issue: 1, Pages: 13421.

Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma

Andrew M Donson,  John Apps,  Andrea M Griesinger,  Vladimir Amani,  Davis A Witt,  Richard C E Anderson,  Toba N Niazi,  Gerald Grant,  Mark Souweidane,  James M Johnston,  Eric M Jackson,  Bette K Kleinschmidt-DeMasters,  Michael H Handler,  Aik-Choon Tan,  Lia Gore,  Alex Virasami,  Jose Mario Gonzalez-Meljem,  Thomas S Jacques,  Juan Pedro Martinez-Barbera,  Nicholas K Foreman,  Todd C Hankinson.

Journal of Neuropathology & Experimental Neurology
Volume: 76, Issue: 9, Pages: 779-788.

TAp73 is a marker of glutamine addiction in medulloblastoma

Maria Victoria Niklison-Chirou,  Ida Erngren,  Mikael Engskog,  Jakob Haglöf,  Daniel Picard,  Marc Remke,  Phelim Hugh Redmond McPolin,  Matthew Selby,  Daniel Williamson,  Steven C. Clifford,  David Michod,  Michalis Hadjiandreou,  Torbjörn Arvidsson,  Curt Pettersson,  Gerry Melino,  Silvia Marino.

Genes & Development
Volume: 31, Issue: 17, Pages: 1738-1753.

miR-128a, miR-130b and miR-155 are co-drivers of T(4;11) Mll-AF4 acute lymphoblastic leukaemia

Camille Malouf,  Franziska Sahm,  Chrysa Kapeni,  Katrin Ottersbach.

Experimental Hematology
Volume: 53, Pages: S80.

Intragenic amplification of PAX5: a novel subgroup in B-cell precursor acute lymphoblastic leukemia?

Claire Schwab,  Karin Nebral,  Lucy Chilton,  Cristina Leschi,  Esmé Waanders,  Judith M. Boer,  Markéta Žaliová,  Rosemary Sutton,  Ingegerd Ivanov Öfverholm,  Kentaro Ohki,  Yuka Yamashita,  Stefanie Groeneveld-Krentz,  Eva Fronková,  Marleen Bakkus,  Joelle Tchinda,  Thayana da Conceição Barbosa,  Grazia Fazio,  Wojciech Mlynarski,  Agata Pastorczak,  Giovanni Cazzaniga,  Maria S. Pombo-de-Oliveira,  Jan Trka,  Renate Kirschner-Schwabe,  Toshihiko Imamura,  Gisela Barbany,  Martin Stanulla,  Andishe Attarbaschi,  Renate Panzer-Grümayer,  Roland P. Kuiper,  Monique L. den Boer,  Hélène Cavé,  Anthony V. Moorman,  Christine J. Harrison,  Sabine Strehl.

Blood Advances
Volume: 1, Issue: 19, Pages: 1473-1477.

Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma

Richard A. Noble,  Natalie Bell,  Helen Blair,  Arti Sikka,  Huw Thomas,  Nicole Phillips,  Sirintra Nakjang,  Satomi Miwa,  Rachel Crossland,  Vikki Rand,  Despina Televantou,  Anna Long,  Hector C. Keun,  Chris M. Bacon,  Simon Bomken,  Susan E. Critchlow,  Stephen R. Wedge.

Haematologica
Volume: 102, Issue: 7, Pages: 1247-1257.

Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

Edward C Schwalbe,  Janet C Lindsey,  Sirintra Nakjang,  Stephen Crosier,  Amanda J Smith,  Debbie Hicks,  Gholamreza Rafiee,  Rebecca M Hill,  Alice Iliasova,  Thomas Stone,  Barry Pizer,  Antony Michalski,  Abhijit Joshi,  Stephen B Wharton,  Thomas S Jacques,  Simon Bailey,  Daniel Williamson,  Steven C Clifford.

The Lancet Oncology
Volume: 18, Issue: 7, Pages: 958-971.

Biallelic TRIP13 mutations predispose to Wilms tumor and chromosome missegregation

Shawn Yost,  Bas de Wolf,  Sandra Hanks,  Anna Zachariou,  Chiara Marcozzi,  Matthew Clarke,  Richarda M. de Voer,  Banafsheh Etemad,  Esther Uijttewaal,  Emma Ramsay,  Harriet Wylie,  Anna Elliott,  Susan Picton,  Audrey Smith,  Sarah Smithson,  Sheila Seal,  Elise Ruark,  Gunnar Houge,  Jonathon Pines,  Geert J. P. L. Kops,  Nazneen Rahman.

Nature Genetics
Volume: 49, Issue: 7, Pages: 1148-1151.

Re-ordering the B cell developmental hierarchy in fetal life; characterisation of a novel human B progenitor

O'Byrne, Sorcha,  Elliott, Natalina,  Buck, Gemma,  Liu, Binbin,  Povinelli, Benjamin,  Fordham, Nicholas,  Louka, Eleni,  Bartolovic, Kerol,  Karadimitris, Anastasios,  Mead, Adam,  Roberts, Irene,  Roy, Anindita.

Volume: 102, Pages: 80-80.

Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification

Felipe Andreiuolo,  Gwénaël Le Teuff,  Mohamed Amine Bayar,  John-Paul Kilday,  Torsten Pietsch,  André O. Von Bueren,  Hendrik Witt,  Andrey Korshunov,  Piergiorgio Modena,  Stefan M. Pfister,  Mélanie Pagès,  David Castel,  Felice Giangaspero,  Leila Chimelli,  Pascale Varlet,  Stefan Rutkowski,  Didier Frappaz,  Maura Massimino,  Richard Grundy,  Jacques Grill,  on behalf of the SIOP Ependymoma Biology Working Group BIOMECA (BIOlogical Markers for Ependymomas in Children and Adolescents).

PLOS ONE
Volume: 12, Issue: 6, Pages: e0178351.

Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification

Felipe Andreiuolo,  Gwénaël Le Teuff,  Mohamed Amine Bayar,  John-Paul Kilday,  Torsten Pietsch,  André O. von Bueren,  Hendrik Witt,  Andrey Korshunov,  Piergiorgio Modena,  Stefan M. Pfister,  Mélanie Pagès,  David Castel,  Felice Giangaspero,  Leila Chimelli,  Pascale Varlet,  Stefan Rutkowski,  Didier Frappaz,  Maura Massimino,  Richard Grundy,  Jacques Grill,  on behalf of the SIOP Ependymoma Biology Working Group BIOMECA (BIOlogical Markers for Ependymomas in Children and Adolescents).

PLOS ONE
Volume: 12, Issue: 6, Pages: e0178351.

Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification

Felipe Andreiuolo,  Gwénaël Le Teuff,  Mohamed Amine Bayar,  John-Paul Kilday,  Torsten Pietsch,  André O. von Bueren,  Hendrik Witt,  Andrey Korshunov,  Piergiorgio Modena,  Stefan M. Pfister,  Mélanie Pagès,  David Castel,  Felice Giangaspero,  Leila Chimelli,  Pascale Varlet,  Stefan Rutkowski,  Didier Frappaz,  Maura Massimino,  Richard Grundy,  Jacques Grill,  on behalf of the SIOP Ependymoma Biology Working Group BIOMECA (BIOlogical Markers for Ependymomas in Children and Adolescents).

PLOS ONE
Volume: 12, Issue: 6, Pages: e0178351.

Genomic architecture and treatment outcome in pediatric acute myeloid leukemia: a Children’s Oncology Group report

Marijana Vujkovic,  Edward F. Attiyeh,  Rhonda E. Ries,  Elizabeth K. Goodman,  Yang Ding,  Marko Kavcic,  Todd A. Alonzo,  Yi-Cheng Wang,  Robert B. Gerbing,  Lillian Sung,  Betsy Hirsch,  Susana Raimondi,  Alan S. Gamis,  Soheil Meshinchi,  Richard Aplenc.

Blood
Volume: 129, Issue: 23, Pages: 3051-3058.

TPMT, COMT and ACYP2 genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity

Signe Thiesen,  Peng Yin,  Andrea L. Jorgensen,  Jieying E. Zhang,  Valentina Manzo,  Laurence McEvoy,  Christopher Barton,  Susan Picton,  Simon Bailey,  Penelope Brock,  Harish Vyas,  David Walker,  Guy Makin,  Srinivas Bandi,  Barry Pizer,  Daniel B. Hawcutt,  Munir Pirmohamed.

Pharmacogenetics and Genomics
Volume: 27, Issue: 6, Pages: 213.

Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma

Lee D. McDaniel,  Karina L. Conkrite,  Xiao Chang,  Mario Capasso,  Zalman Vaksman,  Derek A. Oldridge,  Anna Zachariou,  Millicent Horn,  Maura Diamond,  Cuiping Hou,  Achille Iolascon,  Hakon Hakonarson,  Nazneen Rahman,  Marcella Devoto,  Sharon J. Diskin.

PLOS Genetics
Volume: 13, Issue: 5, Pages: e1006787.

Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma

Lee D. McDaniel,  Karina L. Conkrite,  Xiao Chang,  Mario Capasso,  Zalman Vaksman,  Derek A. Oldridge,  Anna Zachariou,  Millicent Horn,  Maura Diamond,  Cuiping Hou,  Achille Iolascon,  Hakon Hakonarson,  Nazneen Rahman,  Marcella Devoto,  Sharon J. Diskin.